Medikamentöse Therapie der Endometriose

In: Die Gynäkologie · 2026 · doi:10.1007/s00129-026-05522-7 · W7167493993
article OA: closed CC0
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AI-generated summary by claude@2026-07+body, 2026-07-08

This review details drug therapy for endometriosis, recommending individualized, symptom-oriented treatment with progestins and GnRH antagonists as first-line options, and GnRH agonists for refractory cases.

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AI-generated deep summary by claude@2026-07, 2026-07-08

The paper reviews medication-based treatment for endometriosis, focusing on symptom control—especially pain—and suppression of disease activity, based on the current S2k guideline and summarized literature rather than new patient data. It reports that individualized, symptom- and context-oriented therapy should consider the patient’s situation, desire for children, and side-effect profiles, with progestins and oral GnRH antagonists (after prior surgery) as first-line options. GnRH agonists are described as effective for therapy-refractory cases or specific situations but requiring careful side-effect management. This paper is centrally about endometriosis — it outlines guideline-based principles and first-line pharmacologic options for controlling endometriosis-associated pain and disease activity.

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last seen: 2026-07-10T06:00:46.527841+00:00
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