Adjuvant Therapy for Uterine Fibroids and Genital Endometriosis

I.V. Kuznetsova
In: Effective Pharmacotherapy · 2021 · vol. 17(19) , pp. 20–30 · doi:10.33978/2307-3586-2021-17-19-20-30 · W4205331635
article OA: diamond CC0 ⤵ 1 in-corpus citation
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This paper explores lifestyle adjustments, specifically nutritional support with indole-3-carbinol and epigallocatechin-3-gallate, to enhance adjuvant therapy effectiveness for uterine fibroids and endometriosis.

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Abstract

The reproductive system organs’ diseases associated with pathological proliferation have common pathogenetic characteristics due to epigenetic changes in cell populations. With a sufficiently large arsenal of drugs for the treatment of patients with proliferative diseases, there remains dissatisfaction with its results both in terms of achieving the current effect and in terms of reducing long-term risks due to the tendency to the uncontrolled cell growth. In this regard, the search for ways to correct the lifestyle in order to increase the effectiveness of the applied therapies and improve the prognosis of the health of women with diseases associated with excessive proliferation becomes relevant. First of all, we are talking about rational nutrition, which should include the subsidy of biologically active substances known as phytoprotectors of tumor and inflammatory processes. Such biologically active substances include indole-3-carbinol and epigallocatechin-3-gallate, which have long been used as dietary supplements in gynecological practice

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endometriosis

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