CLINICAL ASSISTED REPRODUCTION: Haemodynamic Evaluation of Tubal and Male Factors of Infertility in Natural and Ovarian Stimulation Cycles

In: Journal of Assisted Reproduction and Genetics · 2001 · vol. 18(3) , pp. 125–128 · doi:10.1023/a:1009489518468 · PMID:11411425 · W1853951503
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AI-generated summary by claude@2026-06+body, 2026-06-08

This study found measurable uterine artery blood flow differences between tubal and male infertility in natural cycles, which were abolished after ovarian stimulation.

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This prospective study evaluated pulsatility index (PI) and resistance index (RI) of the uterine and ovarian arteries in women with tubal-factor versus male-factor infertility, comparing natural cycles with ovarian-stimulated cycles. In natural cycles, uterine PI and RI differed between groups, with tubal infertility showing lower uterine PI (3.55 ± 1.39) and similar but distinct uterine RI (0.95 ± 0.05) compared with male-factor infertility. After ovarian stimulation in tubal factor, uterine PI and RI values became similar to those in male-factor infertility, indicating that stimulation abolished the natural-cycle differences. The paper’s limitation is that it focuses on haemodynamic indices rather than direct implantation or pregnancy outcomes, as described in the abstract. This paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Purpose: To determine the haemodynamic parameters in women with tubal and male factors of infertility and to investigate the effect of ovarian stimulation on the blood flow indices of the uterine and ovarian arteries.

Methods

Prospective evaluation of the pulsitility index (PI) and resistance index (RI) of the uterine and ovarian arteries in the tubal and male factors of infertility was done. Comparisons were made between the natural and ovarian stimulation cycles.

Results

In natural cycles, uterine PI was 3.55 ± 1.39 and RI was 0.95 ± 0.05 in tubal infertility. These were significantly lower (uterine PI = 4.13 ± 0.08; uterine RI = 0.99 ± 0.06) than the corresponding indices in patients with male factor infertility. After ovarian stimulation in tubal factor, uterine PI and RI were 2.62 ± 0.73 and 0.88 ± 0.08 and were similar (PI = 2.55 ± 0.62, RI = 0.87 ± 0.06) to male factor infertility.

Conclusions

The data points to measurable differences in the uterine PI and RI between the tubal infertility and male infertility in the natural cycles. These differences were abolished after ovarian stimulation. Similar content being viewed by others

References

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