[Results of IVF in women with endometriosis].

F. Olivennes, Olivennes F
Journal de gynecologie, obstetrique et biologie de la reproduction · 2003 · vol. 32(8 Pt 2) , pp. S45–7 · PMID:14968069 · W2247545451
article OA: closed CC0 ⤵ 15 in-corpus citations
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This study investigated IVF outcomes in women with endometriosis, finding that severe disease negatively impacts ovarian reserve and pregnancy rates, while surgical treatment may improve results, particularly for younger women.

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Abstract

When associated with infertility, endometriosis often requires in vitro fertilization (IVF). The need of IVF instead of other Assisted Reproductive Technologies is correlated with the severity of the lesions and associated tubal pathology. Results of IVF (in terms of pregnancy rates), are influenced by the existence of endometriosis, but this influence remains controversial, and focused on three possible points: poor ovarian reserve (and ovarian response), poor quality of oocytes and embryos, poor implantation. It seems that mild and moderate endometriosis (I-II American Fertility Society score) has few deleterious effect on ovarian reserve, ovarian response, and pregnancy rates. All these parameters are decreased by the existence of severe endometriosis (III-IV AFS). Its surgical treatment appears to improve the results of IVF, notably in women under 35. But iterative surgery of endometriomas might be deleterious for ovarian function. Previous treatment by Gn-RH agonists also improves the outcome of IVF, whereas ICSI does not modify either the biological parameters, nor the pregnancy rates. Ovarian hyperstimulation in women with endometriosis might increase the severity of the lesions and the risk of complications: the use of unstimulated cycle (n-IVF) in young patients with normal ovarian reserve might be interesting.

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Condition tags

endometriosisinfertility

MeSH descriptors

Endometriosis Endometriosis Fertilization in Vitro Female Fertilization in Vitro Fertilization in Vitro Humans Infertility, Female Infertility, Female Infertility, Female Ovary Ovary

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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