Transmission and prevention of uterine dysfunction in daughters of dioxin-exposed male mice

article OA: hybrid public-domain-us
AI-generated summary by qwen3.7-flash, 2026-08-21

A mouse model demonstrates that uterine dysfunction resembling endometriosis can be transmitted from fathers to daughters, potentially via an epigenetic pathway amenable to therapeutic intervention.

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Abstract

In brief: Daughters of women with endometriosis are known to be at increased risk of developing this disease. Using a mouse model, we demonstrate that uterine dysfunction reminiscent of that in endometriosis patients can also be passed from the father to the daughter, potentially via an epigenetic pathway amenable to therapeutic intervention.

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MeSH descriptors

Dioxins Dioxins Dioxins Dioxins Dioxins Dioxins Dioxins Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Uterine Diseases Uterine Diseases Uterine Diseases Uterine Diseases Uterine Diseases Uterine Diseases

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Source provenance

europepmc
last seen: 2026-08-28T06:11:01.063540+00:00
openalex
last seen: 2026-08-28T06:02:16.119096+00:00
pubmed
last seen: 2026-08-28T06:03:56.646171+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine