Medicated intrauterine systems for treatment of endometriosis-associated pain

Ludovico Muzii
Journal of Minimally Invasive Gynecology · 2006 · vol. 13(6) , pp. 535–538 · doi:10.1016/j.jmig.2006.06.010 · PMID:17097576 · W2083380976
review OA: closed CC0 ⤵ 3 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This review examines the efficacy and safety of medicated intrauterine systems for managing endometriosis-associated pain.

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Abstract

Medicated intrauterine systems (IUSs) are intrauterine devices that act by means of the local release of a medication. The levonorgestrel (LNG)-IUS is a T-shaped device that releases the progestogen LNG directly into the uterine cavity. The LNG-IUS can be used with noncontraceptive, therapeutic intent for idiopathic menorrhagia, hormonal replacement therapy in conjunction with oral or transdermal estrogens, and endometriosis or adenomyosis-associated pain. For this last indication, however, the use of the LNG-IUS is still under clinical investigation.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Drug Delivery Systems Endometriosis Intrauterine Devices Pelvic Pain Contraceptive Agents, Female Contraceptive Agents, Female Endometriosis Endometriosis Female Humans Levonorgestrel Levonorgestrel Menorrhagia Menorrhagia Pelvic Pain Pelvic Pain Pelvic Pain

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (23)

Cited by (3)

Source provenance

europepmc
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License: CC0 · commercial use OK