Comprehensive Review: Various Clinical and Radiologic Manifestations of Endometriosis

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This poster presents a comprehensive review of the diverse clinical and radiologic manifestations of endometriosis.

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This educational exhibit reviews the diverse clinical and radiologic presentations of endometriosis, emphasizing that imaging characteristics vary widely depending on hormonal responses during the menstrual cycle. The authors detail both typical manifestations, such as peritoneal implants and ovarian endometriomas, and unusual sites including the gastrointestinal and genitourinary tracts, while discussing differential diagnoses for mimicking lesions. The paper highlights that familiarity with these varied features across ultrasound, CT, and MRI modalities is essential for accurate diagnosis and treatment planning. This paper is centrally about endometriosis — specifically its diagnostic imaging manifestations across various anatomical sites.

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Abstract

Poster: ECR 2014 / C-1322 / Comprehensive Review: Various Clinical and Radiologic Manifestations of Endometriosis by: H. Han, S. B. Park; Seoul/KR
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Keywords

Genital / Reproductive system female, MR, Ultrasound, CT, Decision analysis, Imaging sequences, Education and training, Tissue characterisation Authors: B. H. Han, S. B. Park; Seoul/KR DOI: 10.1594/ecr2014/C-1322 Learning objectives Learning Objectives: 1. Describe the various clinical and imaging manifestations of endometriosis. 2. Identify which imaging features are more specific for endometriosis. 3. Discuss MR strategies for identification and characterization of endometriosis. 4. Identify unusual imaging features and involving sites.

Background

Endometriosis is an important gynecologic disorder primarily affecting women during their reproductive years, and defined as functional endometrium located outside the uterus. The clinical manifestations may provide only limited information which often overlaps that of other diseases, and are protean, from asymptomatic to the disabling chronic pelvic pain. The three hallmarks of endometriosis are peritoneal endometrial implants inperitoneal cavity, endometriomas(endometriotic cysts)in ovary, and adhesions. Pathogenesis: Three theories of histogenesis have been proposed: (a) metastatic theory (retrograde menstrual implantation, vascular and lymphatic spread, and intraoperative implantation),... Findings and procedure details In this exhibit, we demonstrate the usual and unusual manifestations of endometriosis. Usual manifestations include radiologic diagnostic strategies according modalities and clinical issues such as adhesion, malignant transformation, deep pelvic endometriosis, rupture, decidualized endometriosis, associated with uterine anomaly, and associated with adenomyosis. Unusual manifestations include gastrointestinal tract (rectosigmoid colon, appendix), genitourinary tract (bladder, ureter), chest, subcutaneous and muscular lesion (abdominal wall, perineum) and vagina. We also discuss possible differential point from various mimicking ovarian cystic lesions such as hemorrhagic cyst, mucinous tumor.

Conclusion

The major teaching points of this exhibit are: 1. The imaging characteristics of endometriosis vary widely, with masses ranging from cystic to solid and complex, which depend on the hormonal response of the ectopic tissue during the menstrual cycle. 2. Familiarity with the clinical setting and imaging feature of both usual and unusual endometriosis as depicted with US, CT, and MR will facilitate prompt and accurate diagnosis and treatment. Personal information Byoung Hee Han, MD1, Sung Bin Park, MD2 1Department of Radiology, Cheil General Hospital & Women’s Healthcare Center, Kwandong University College of Medicine, 1-19 Mukjeong-dong, Jung-gu, Seoul, 100-380, Korea 2Department of Radiology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, 224-1, Heukseok-dong, Dongjak-gu, Seoul, 156-755, Korea

References

1. Park SB, Kim JK, Cho KS. Sonography of endometriosis in infrequent sites. J Clin Ultrasound 2008;36:91–97 2. Woodward PJ, Sohaey R, Mezzetti, Jr, TP. Endometriosis: Radiologic-pathologic correlation. RadioGraphics 2001; 21:193–216 3. Choudhary S, Fasih N, Papadatos D, et al. Unusual imaging appearances of endometriosis. AJR 2009; 192:1632–1644 4.Bennett GL,Slywotzky CM, Cantera M, et al. Unusual manifestations and complications of endometriosis—spectrum of imaging findings: pictorial review. AJR 2010;194:WS34–WS46

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