Arias-Stella reaction as a diagnostic pitfall in a bladder biopsy with endometriosis: Case report and review of the pseudoneoplastic bladder lesions

Kiril Trpkov, Guggisberg K, Kelly Guggisberg, Asli Yilmaz, Aslı Yilmaz, Yilmaz A
Pathology, research and practice · 2009 · vol. 205(9) , pp. 653–656 · doi:10.1016/j.prp.2008.12.016 · PMID:19195797 · W2021930584
article OA: closed CC0 ⤵ 3 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-12 ⓘ

This case report describes a bladder biopsy with endometriosis that mimicked a pseudoneoplastic lesion, highlighting the Arias-Stella reaction as a potential diagnostic pitfall.

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Abstract

Arias-Stella reaction is a hormone-induced atypical endometrial change that may involve endometrial, extraendometrial, or endometriotic sites. Establishing a correct diagnosis of Arias-Stella reaction may sometimes be problematic when seen outside of the uterine corpus, particularly in a limited biopsy sample when the pathologist is not aware of the clinical history. We report an Arias-Stella reaction in bladder endometriosis, which presented as a bladder mass in a 25-year-old pregnant woman. Clinical information of intrauterine pregnancy (week 16) was not initially provided when the biopsy was performed. We also discuss endometriosis, endocervicosis, and müllerianosis of the bladder, which are benign glandular lesions that may mimic tumors within the bladder wall.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Pregnancy Complications Urinary Bladder Diseases Adult Biopsy Diagnosis, Differential Endometriosis Endometriosis Female Humans Pregnancy Pregnancy Complications Pregnancy Complications Urinary Bladder Diseases Urinary Bladder Diseases Urinary Bladder Neoplasms Urinary Bladder Neoplasms

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (18)

Cited by (3)

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europepmc
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