Endometriosis and Inflammatory Bowel Diseases

Pauline Wils, Lucas Guillo, Oumaya El Oumami, P. Verpillat, Chrystèle Rubod
In: Hépato-Gastro & Oncologie Digestive · 2026 · vol. 33(3) , pp. 347–354 · doi:10.1684/hpg.2026.3127 · W7143496841
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

Endometriosis and inflammatory bowel disease are distinct conditions of reproductive-aged women that can coexist, presenting diagnostic and therapeutic challenges due to overlapping symptoms and treatment considerations.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text ⓘ

This paper discusses the relationship between endometriosis and chronic inflammatory bowel diseases (IBD/MICI) in women of reproductive age, focusing on how these conditions can coexist and thereby complicate diagnosis and management. It highlights that clinical manifestations overlap frequently, including pelvic or abdominal pain, bowel transit disturbances, and rectal bleeding, making symptom attribution to either condition difficult. A major caveat is that the paper is narrative/editorial in nature, presenting clinical challenges and care roles rather than reporting original empirical data or specific outcomes. Relevance to endometriosis: the paper is explicitly about endometriosis alongside chronic intestinal inflammatory diseases, emphasizing overlapping symptoms and diagnostic/therapeutic challenges when endometriosis coexists with IBD, though it is not limited to endometriosis alone.

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Abstract

Endometriosis affects approximately 10% of women of reproductive age. Inflammatory bowel disease (IBD) predominantly affects a young population, also of reproductive age, with a rising prevalence. Although these two conditions are physiopathologically distinct, they may coexist in the same patient, thereby complicating diagnosis and management. This coexistence represents a significant diagnostic challenge, as their clinical manifestations frequently overlap—including pelvic or abdominal pain, bowel habit disturbances, and rectal bleeding—making it difficult to attribute symptoms to one condition or the other. Their coexistence also raises therapeutic challenges, particularly when symptoms persist despite well-managed IBD treatment, or when surgical intervention for digestive endometriosis is being considered. The role of the gastroenterologist is crucial in managing patients with both IBD and endometriosis, especially when digestive involvement is present or in the postoperative course following endometriosis-related digestive surgery.
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Hépato-Gastro & Oncologie Digestive MENUEndométriose et maladies inflammatoires chroniques de l’intestin Volume 33, numéro 3, Mars 2026 - Mots-clés : maladies inflammatoires chroniques de l’intestin, endométriose, muldisciplinaire - DOI : 10.1684/hpg.2026.3127 - Page(s) : 347-54 - Année de parution : 2026 L’endométriose affecte environ 10 % des femmes en âge de procréer. Les maladies inflammatoires chroniques de l’intestin (MICI) concernent majoritairement une population jeune, en âge de procréer, avec une prévalence croissante. Bien que distinctes d’un point de vue physiopathologique, ces deux maladies peuvent coexister chez une même patiente, complexifiant ainsi le diagnostic et la prise en charge. Cette situation constitue un défi diagnostique, les manifestations cliniques se recoupant fréquemment (douleurs pelviennes ou abdominales, troubles du transit, rectorragies) rendant difficile l’attribution des symptômes à l’une ou l’autre des maladies. Cette coexistence soulève des enjeux thérapeutiques, notamment en cas de symptômes persistants malgré le traitement de la MICI bien conduit, ou lorsqu’une intervention chirurgicale pour endométriose digestive est envisagée. Le rôle du gastroentérologue est important dans la prise en charge des patientes présentant à la fois une MICI et une endométriose (surtout dans les formes avec une atteinte digestive ou dans les suites d’une cure chirurgicale digestive).

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