Endometriosis and fertility: current state of the issue

The paper is a narrative overview examining the epidemiology and reproductive implications of endometriosis, focusing on fertility and pregnancy course, and summarizes population-level prevalence/incidence figures in the world and in Russia using published sources and official monitoring/statistics, with attention to regional trends such as a reported rise in Stavropol Krai. It highlights that endometriosis is highly prevalent among women of reproductive age (often cited as ~10–15%) and is substantially more common among patients with infertility (reported up to ~30–50%), while mechanisms proposed to affect fertility include chronic inflammation, hormonal dependence, and likely multifactorial pathways (with anatomical distortion and other processes mentioned). A key limitation acknowledged implicitly is that prognostic prediction for fertility outcomes remains insufficiently studied and that diagnostic/registration data may be influenced by underdiagnosis and changing detection awareness. This paper is centrally about endometriosis — it reviews how endometriosis affects fertility and pregnancy outcomes and summarizes Russian and global burden estimates relevant to reproductive health.

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