Necrotising granulomas of the uterine corpus

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Four patients developed necrotising granulomas of the uterine corpus with black foreign material following transcervical laser ablation, a histological pattern resulting from tissue fulguration rather than infection.

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Abstract

Necrotising granulomatous inflammation of the uterine corpus associated with transcervical laser ablation of the endometrium occurred in four patients. The abnormalities seen, including extensive necrosis and hyalinisation with foreign body giant cells containing black foreign material, and eosinophilic homogenisation around blood vessels, were due to the effects of tissue fulguration. The presence of black foreign material in loosely organised histiocytes should alert the pathologist even in the absence of clinical information; stains for organisms are negative.

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MeSH descriptors

Granuloma Uterine Diseases Adult Endometrium Endometrium Endometrium Female Granuloma Granuloma Humans Laser Therapy Middle Aged Myometrium Myometrium Postoperative Complications Postoperative Complications Uterine Diseases Uterine Hemorrhage Uterine Hemorrhage

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europepmc
last seen: 2026-10-11T09:27:45.537177+00:00
pubmed
last seen: 2026-10-08T21:59:25.815134+00:00