Wpływ karmienia piersią na rozwój endometriozy.

In: Fides et Ratio, Vol 43, Iss 3 (2020) · 2020 · vol. 43(3) , pp. 364–372 · doi:10.34766/fetr.v43i3.316 · W3102977013
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This review examines scientific evidence linking breastfeeding to the risk, pathogenesis, and potential prevention of endometriosis by considering its long-term hormonal, immunological, and epigenetic effects on women.

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This review examines the potential protective role of breastfeeding against endometriosis by analyzing how lactation influences the female endocrine system and immune programming. The authors discuss scientific evidence linking prolonged breastfeeding to reduced risk, suggesting that the hormonal changes during pregnancy and lactation may alter disease etiopathogenesis through epigenetic mechanisms. The paper highlights the importance of this relationship for developing prophylactic strategies and educating medical professionals on preventive health measures. This paper is centrally about endometriosis — specifically focusing on breastfeeding as a modifiable environmental factor influencing its development and prevention.

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Abstract

Patogeneza endometriozy wynika z współdziałania czynników środowiskowych i genetycznych. Ze względu na częste występowanie oraz duży wpływ na życie i stan zdrowia, ustalenie ważnych czynników sprawczych endometriozy jest istotnym problemem zdrowia publicznego. Do ciekawych zjawisk, niewątpliwie wpływających na ryzyko endometriozy należy karmienie piersią. Ciąża i laktacja jest istotnym elementem cyklu prokreacyjnego wpływającym gruntownie na całą gospodarkę endokrynologiczną kobiety z konsekwencjami trwającymi lata. Z drugiej strony możliwość karmienia się pokarmem matki jest dla dziecka najlepszym źródłem składników odżywczych, ale również sygnałem programującym immunologicznie i epigenetycznie organizm na okres całego życia. Poniżej przedstawiono koncepcje i dowody naukowe wiążące karmienie piersią z ryzykiem występowania i etiopatogenezą endometriozy. Świadomość możliwych związków przyczynowych w tej dziedzinie jest kluczowa nie tylko dla leczenia pacjentek z endometriozą, lecz ma znaczenie w budowaniu strategii profilaktycznych niezbędnych w zapobieganiu tej chorobie. Zaprezentowana wiedza jest również pomocna dla profesjonalistów medycznych biorących udział w konsultowaniu i edukacji prozdrowotnej pacjentek.
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Abstract

The pathogenesis of endometriosis depends on the interaction of environmental and genetic factors. Due to its high prevalence and major impact on quality of life and health, identifying important causative agents of endometriosis is a major public health concern. One of the interesting phenomena that undoubtedly influences the risk of endometriosis is breastfeeding. Pregnancy and lactation is an important element of the reproductive cycle that has a profound effect on the entire endocrine system of a woman, with long-lasting consequences. On the other hand, the possibility of feeding on the mother's food is the best source of nutrients for the baby, but also a signal that programs the body immunologically and epigenetically throughout its entire life. The concepts and scientific evidence linking breastfeeding with the risk and etiopathogenesis of endometriosis are presented below. Awareness of possible causal relationships in this field is crucial not only for the treatment of patients with endometriosis but also for building prophylactic strategies necessary to prevent this disease. The presented knowledge is also helpful for medical professionals participating in consulting and pro-health education of patients.

References

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