Letter to the Editor
This letter identifies methodological concerns regarding studies on non-invasive imaging for deep endometriosis, including bias from laparoscopy inclusion, unknown prevalence impact on predictive values, and the formulation of consensus opinions.
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This Letter to the Editor comments on an International Consensus Statement compiling sensitivities, specificities, and likelihood ratios for non-invasive imaging in diagnosing pelvic deep endometriosis, arguing that the underlying studies have overall poor methodological quality. The author notes key limitations: results are conditional on laparoscopy being performed (which may bias included participants), and lack of blinding could allow imaging results to influence the decision to perform surgery, leaving false negatives and negative predictive values unknown and possibly inflating sensitivity and specificity. The letter also emphasizes that prevalence was not considered for predictive value interpretation, urging discussion of inclusion criteria, prevalence assumptions for PPVs, and how experience is defined when consensus opinions are used to grade evidence. This paper is centrally about endometriosis — it critiques the methodological and statistical validity of non-invasive imaging evidence for diagnosing pelvic deep endometriosis.
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Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (8)
- A proof of concept that experience-based management of endometriosis can complement evidence-based guidelines via openalex
- Imaging modalities for the non-invasive diagnosis of endometriosis via openalex
- Non-invasive imaging techniques for diagnosis of pelvic deep endometriosis and endometriosis classification systems: an International Consensus Statement†,‡ via openalex
- Predictive Value of Ultrasound Imaging for Diagnosis and Surgery of Deep Endometriosis: A Systematic Review via openalex
- Preoperative imaging of deep endometriosis: pitfalls of a diagnostic test before surgery. via openalex
- The title is misleading: an opinion paper is not a consensus paper via openalex
- W4399070239 via openalex
- W2482566988 via openalex
Source provenance
- europepmc
- last seen: 2026-06-24T06:10:11.469335+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00