Neuropathic Pain in Patients with Endometriosis — Diagnosis and Treatment: Comparative Prospective Study

М. Н. Шаров, A.S. Chernetsova, L.V. Adamyan, K.D. Murvatov, S.I. Kiselev, Y.S. Prokofieva, И. Н. Гончаров
In: Comorbidity neurology · 2024 · vol. 1(2) , pp. 5–14 · doi:10.62505/3034-185x-2024-1-2-5-14 · W4399086786
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This study found that complex therapy, including muscle relaxants, effectively reduced neuropathic pain in endometriosis patients, while progestogen-only hormonal therapy was less effective.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This comparative prospective study evaluated diagnostic and treatment outcomes in 65 women aged 18–45 with histologically verified endometriosis who had chronic pelvic pain with a neuropathic component and neuropathy. The authors report that complex therapy reduced pain intensity by 89% among patients with neuropathic pain due to endometriosis, while hormonal therapy using only a progestagen was less effective in this subgroup. The paper concludes that adding a muscle relaxant is effective for chronic pelvic pain with a neuropathic component in endometriosis, with an explicit limitation being that the provided summary does not detail study design specifics such as randomization or control conditions. This paper is centrally about endometriosis — it investigates diagnosis and comparative treatment effectiveness for neuropathic pain in women with endometriosis.

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Abstract

INTRODUCTION. Chronic pelvic pain is the most common symptom of endometriosis. The neuropathic component of chronic pain has a significant impact on all areas of patients’ lives. AIM. To increase the effectiveness of treatment of patients with chronic pelvic pain with a neuropathic component due to endometriosis. MATERIAL AND METHODS. A comparative analysis of the results of examination and treatment of 65 women (18–45 years old) with a histologically verified diagnosis of endometriosis, suffering from chronic pelvic pain and neuropathy was carried out. RESULTS AND DISCUSSION. The use of complex therapy reduced pain intensity by 89% in patients with neuropathy due to indometriosis. Progestogen-only hormonal therapy is less effective for patients suffering from chronic pelvic pain with a neuropathic component due to endometriosis. CONCLUSION. The use of a muscle relaxant is effective for chronic pelvic pain with a neuropathic component in endometriosis. KEYWORDS: endometriosis, chronic pelvic pain, neuropathic pain, depression

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endometriosischronic_pelvic_pain

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