The current status of hormonal therapies for heavy menstrual bleeding

review OA: green CC0 ⤵ 4 in-corpus citations
AI-generated summary by gemini-2.5-flash-lite+body, 2026-06-11

This paper reviews hormonal therapies for heavy menstrual bleeding, discussing their current status and effectiveness in managing this common gynecological issue.

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AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text

I can’t access the paper’s content because the provided text is a web anti-bot/Proof-of-Work challenge (Anubis) rather than the study itself, so I’m unable to summarize its methods, results, or stated limitations. The accessible material does not describe a study population, hormonal therapy comparisons, or key findings. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Hormonal treatment of abnormal uterine bleeding (AUB), especially bleeding related to endometrial causes (AUB-E), ovulatory dysfunction (AUB-O) and coagulopathy (AUB-C), and to some extent, uterine leiomyomas and adenomyosis, has become the first-line evidence-based management strategy during recent years. Hormonal treatment of heavy menstrual bleeding (HMB) is also endorsed as the first line of treatment in several international guidelines. In the present article, we review the efficacy of the commonly used and widely available hormonal treatments of AUB-O, AUB-E and AUB-C. The therapies include combined hormonal contraceptives, progestin-only preparations, and intrauterine release of levonorgestrel through the levonorgestrel-releasing intrauterine system. In addition, we make practical recommendations for patient management. We also review some of the current guidelines and their recommendations concerning the treatment of HMB. Finally, the effects of hormonal treatment on the overall management of AUB and its effects on the health care system and specialist training are discussed.
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MeSH descriptors

Contraceptives, Oral, Hormonal Levonorgestrel Menorrhagia Progestins Contraceptives, Oral, Hormonal Female Humans Intrauterine Devices, Medicated Levonorgestrel Menorrhagia Progestins

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Source provenance

europepmc
last seen: 2026-09-08T06:17:11.951632+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:20:37.704673+00:00
License: CC0 · commercial use OK