Catamenial hemoptysis and pneumothorax in a patient with cystic fibrosis

Case report OA: gold CC0 ⤵ 7 in-corpus citations
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

This case report describes a cystic fibrosis patient diagnosed with thoracic endometriosis syndrome based on recurrent catamenial hemoptysis and pneumothoraces, which resolved after medical treatment and lung transplantation.

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Abstract

Hemoptysis or pneumothorax that recurs with the onset of menses is strongly suggestive of thoracic endometriosis syndrome (TES). TES is a rare disorder, with relatively few cases reported in the literature. A 32-year-old woman with cystic fibrosis, who over a period of several months had experienced recurrent catamenial hemoptysis and pneumothoraces, including an episode of life-threatening hemoptysis that coincided with menstruation, is presented. Thoracic computed tomography and magnetic resonance imaging scans, as well as a bronchoscopic evaluation that demonstrated endobronchial lesions that disappeared after menses, support the diagnosis of TES in the present patient. The patient was treated empirically with danazol and subsequently underwent a successful double-lung transplantation. Danazol was discontinued postoperatively, and she was started on an oral contraceptive. Eighteen months post-transplant, she has not experienced a recurrence of her catamenial symptoms, despite having resumed a regular menstrual cycle.

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Condition tags

endometriosisthoracic_endometriosis

MeSH descriptors

Cystic Fibrosis Endometriosis Hemoptysis Menstruation Menstruation Pneumothorax Adult Adult Cystic Fibrosis Cystic Fibrosis Danazol Danazol Danazol Endometriosis Endometriosis Endometriosis Endometriosis Estrogen Antagonists Estrogen Antagonists Estrogen Antagonists

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (15)

Cited by (6)

Source provenance

europepmc
last seen: 2026-10-12T06:17:10.165071+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:04:39.942088+00:00
License: CC0 · commercial use OK