Catamenial Hemoptysis and Pneumothoraces in a Patient with Cystic Fibrosis

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AI-generated summary by claude@2026-06, 2026-06-08

This case report describes a cystic fibrosis patient diagnosed with thoracic endometriosis syndrome based on recurrent catamenial hemoptysis and pneumothoraces, which resolved after medical treatment and lung transplantation.

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Abstract

Hemoptysis or pneumothorax that recurs with the onset of menses is strongly suggestive of thoracic endometriosis syndrome (TES). TES is a rare disorder, with relatively few cases reported in the literature. A 32-year-old woman with cystic fibrosis, who over a period of several months had experienced recurrent catamenial hemoptysis and pneumothoraces, including an episode of life-threatening hemoptysis that coincided with menstruation, is presented. Thoracic computed tomography and magnetic resonance imaging scans, as well as a bronchoscopic evaluation that demonstrated endobronchial lesions that disappeared after menses, support the diagnosis of TES in the present patient. The patient was treated empirically with danazol and subsequently underwent a successful double-lung transplantation. Danazol was discontinued postoperatively, and she was started on an oral contraceptive. Eighteen months post-transplant, she has not experienced a recurrence of her catamenial symptoms, despite having resumed a regular menstrual cycle.

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Condition tags

endometriosisthoracic_endometriosis

MeSH descriptors

Cystic Fibrosis Endometriosis Hemoptysis Menstruation Pneumothorax Adult Cystic Fibrosis Danazol Danazol Endometriosis Endometriosis Endometriosis Estrogen Antagonists Estrogen Antagonists Female Hemoptysis Hemoptysis Hemoptysis Humans Lung Transplantation

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References (15)

Cited by (7)

Source provenance

europepmc
last seen: 2026-06-13T06:22:48.782012+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:14:48.452140+00:00
License: CC0 · commercial use OK