Well-Differentiated Papillary Mesothelioma With Two Synchronous Serous Gynaecologic Carcinomas in a 62-Year-Old Woman: Lessons Learned for the Gynaecologic Surgeon

Justin M. McGinnis, Bloomfield V, Valerie Bloomfield, Hamid Kazerouni, Kazerouni H, Limor Helpman
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC · 2020 · vol. 42(10) , pp. 1262–1266 · doi:10.1016/j.jogc.2019.12.012 · PMID:32173236 · W3012356850
article OA: closed CC0
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

This case report describes a rare instance of well-differentiated papillary mesothelioma co-occurring with two synchronous serous gynecologic carcinomas in a 62-year-old woman, highlighting surgical considerations.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

BackgroundWell-differentiated papillary mesothelioma (WDPM) is a rare tumor of unknown malignant potential. It is typically diagnosed incidentally during benign gynaecologic surgery. We report the first published case of WDPM in a woman with synchronous serous carcinomas of the gynaecologic tract and highlight lessons learned for general gynaecologists and gynaecologic oncologists alike.CaseA 62-year-old woman was referred for assessment and management of a pelvic mass. Intraoperatively, metastatic high-grade carcinoma was identified and the patient underwent a successful debulking procedure that identified 3 synchronous tumors: ovarian high-grade serous carcinoma, endometrial serous carcinoma, and 2 foci of pelvic WDPM.ConclusionThis case of WDPM with 2 synchronous serous gynaecologic tumors is a novel addition to the reported literature and offers many learning points about the disease. Gynaecologic surgeons should be familiar with WDPM, as it is predominantly found in reproductive-aged women undergoing benign gynaecologic surgery, may be linked with endometriosis, and has an unclear malignant potential. Multidisciplinary care is essential for accurate diagnosis. Further research is needed to clarify the optimal management and surveillance of WDPM.

My notes (saved in your browser only)

MeSH descriptors

Antineoplastic Agents Cystadenocarcinoma, Serous Genital Neoplasms, Female Hysterectomy Mesothelioma Antineoplastic Agents Carboplatin Carboplatin Cystadenocarcinoma, Serous Cystadenocarcinoma, Serous Endometrial Neoplasms Female Genital Neoplasms, Female Genital Neoplasms, Female Humans Mesothelioma Mesothelioma Middle Aged Paclitaxel Paclitaxel

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cites (3)

References (13)

Source provenance

europepmc
last seen: 2026-08-10T06:11:17.106188+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:22:11.167363+00:00
License: CC0 · commercial use OK