A Case Report of Ovarian Fibrothecoma in a Premenopausal Women with Recurrent Menorrhagia

In: Open Access Macedonian Journal of Medical Sciences · 2020 · vol. 8(C) , pp. 101–105 · doi:10.3889/oamjms.2020.4176 · W3099271422
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This case report details a 46-year-old premenopausal woman with recurrent menorrhagia who was diagnosed with ovarian fibrothecoma following a hysterectomy with bilateral salpingo-oophorectomy.

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This case report describes a 46-year-old premenopausal woman with recurrent menorrhagia over two years, who previously underwent two curettage procedures and had no prior gynecologic history. Ultrasound found a homogeneous solid right ovarian mass, and endometrial curettage showed simple endometrial hyperplasia without atypia; she then underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy. Histopathology confirmed ovarian fibrothecoma with proliferative endometrium/hyperplasia without atypia and multiple uterine fibroids, and the authors discuss diagnostic evaluation and surgical management along with a brief literature review. As a single-patient report, it cannot establish prevalence or generalizable diagnostic strategies. This paper does not specifically discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match for endometriosis/adenomyosis–related gynecologic conditions.

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Abstract

BACKGROUND: Ovarian fibrothecoma is a rare, benign, sex cord-stromal neoplasm, with a typically unilateral location in the ovary, characterized by mixed features of both fibroma and thecoma. Ovarian fibrothecoma is uncommon tumor of gonadal stromal cell origin accounting for 3-4% of all ovarian tumours. CASE PRESENTATION: We presented a rare case of a 46-year-old patient with recurrent menorrhagia in the past two years with no previous medical, surgical or gynecological history. She underwent two times curettage procedures. At the admission to hospital ultrasonography showed a homogenous solid right ovarian mass of size 2.5 cm x 3.5 cm. Endometrial curettage revealed simple hyperplasia of the endometrium. Diagnostic evaluation and surgical management are discussed along with a brief review of the literature. Total abdominal hysterectomy with bilateral salpingo-oophorectomy was carried out. Histopathology confirmed fibrothecoma of the ovary, proliferative endometrium with hyperplasia without atypia and multiple uterine fibroids. CONCLUSION: In all patients presenting with recurrent menorrhagia and adnexal tumor the possibility of a granulosa cell tumor must be kept in mind during evaluation.
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Background

Ovarian fibrothecoma is a rare, benign, sex cord-stromal neoplasm, with a typically unilateral location in the ovary, characterized by mixed features of both fibroma and thecoma. Ovarian fibrothecoma is uncommon tumor of gonadal stromal cell origin accounting for 3-4% of all ovarian tumours. CASE PRESENTATION: We presented a rare case of a 46-year-old patient with recurrent menorrhagia in the past two years with no previous medical, surgical or gynecological history. She underwent two times curettage procedures. At the admission to hospital ultrasonography showed a homogenous solid right ovarian mass of size 2.5 cm x 3.5 cm. Endometrial curettage revealed simple hyperplasia of the endometrium. Diagnostic evaluation and surgical management are discussed along with a brief review of the literature. Total abdominal hysterectomy with bilateral salpingo-oophorectomy was carried out. Histopathology confirmed fibrothecoma of the ovary, proliferative endometrium with hyperplasia without atypia and multiple uterine fibroids.

Conclusion

In all patients presenting with recurrent menorrhagia and adnexal tumor the possibility of a granulosa cell tumor must be kept in mind during evaluation. Downloads Metrics Plum Analytics Artifact Widget Block

References

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Case Rep Obst Gynecol. 2013;2013:189072. https://doi. org/10.1155/2013/189072 PMid:23431489 Downloads Published How to Cite Issue Section Categories License Copyright (c) 2020 Meral Rexhepi, Elizabeta Trajkovska, Hysni Ismaili, Majlinda Azemi (Author) This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0)

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