Two kinds of endometrial neoplasia arising from different origins in the uterine corpus: comparison of p53 expression and sex steroid receptor status

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This study compared p53 expression and sex steroid receptor status in two distinct types of endometrial neoplasia, investigating their different origins within the uterine corpus.

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Abstract

This study presents a case of endometrial clear cell adenocarcinoma complicated by complex atypical glandular hyperplasia surrounded by adenomyosis in the uterine myometrium. The former was immuno-negative for estrogen receptor (ER) and positive for p53, whereas both of the latter were immuno-positive for ER and negative for p53. Therefore, there were two kinds of neoplasia arising from different origins in the uterine corpus.

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma, Clear Cell Endometrial Neoplasms Endometriosis Receptors, Estrogen Tumor Suppressor Protein p53 Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Aged Endometrial Hyperplasia Endometrial Hyperplasia Endometrial Hyperplasia Endometrial Hyperplasia Endometrial Neoplasms Endometrial Neoplasms Endometrial Neoplasms Endometriosis Endometriosis Endometriosis Female

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Cites (1)

References (16)

Source provenance

europepmc
last seen: 2026-08-29T06:12:09.280863+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:13:01.552487+00:00
License: CC0 · commercial use OK