Reproductive outcomes of infiltrative endometriosis after surgical treatment with assisted reproductive technologies (a clinical case)

In: Tumors of female reproductive system · 2024 · vol. 20(1) , pp. 139–142 · doi:10.17650/1994-4098-2024-20-1-139-142 · W4398175673
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This case report details the successful management of endometriosis-associated infertility using assisted reproductive technologies, leading to a clinical pregnancy and live birth.

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This paper reports a clinical case on reproductive outcomes for a woman with infiltrative endometriosis-associated infertility managed with surgical treatment followed by assisted reproductive technologies (ART). It describes management decisions based on factors including endometriosis localization, patient age, ovarian reserve, infertility duration, prior therapy and response, fallopian tube status, and semen parameters, with the abstract stating that the chosen approach resulted in a clinical pregnancy and the birth of a healthy child. The main limitation is that it is a single-case report, so no comparative effectiveness of surgical versus nonsurgical strategies for ART can be concluded. This paper is centrally about endometriosis — it focuses on reproductive outcomes of infiltrative endometriosis after surgery using ART.

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Abstract

Endometriosis is one of the most urgent problems of modern gynecology and reproductive medicine. About 40 % of women suffering from endometriosis of various localization are infertile. The use of drug therapy has not been proven to increase fertility. Currently, there is no consensus on the impact of surgical treatment on the effectiveness of assisted reproductive technologies.This article presents a clinical case of modern approache to the use of assisted reproductive technologies for endometriosis-associated infertility. The tactics of managing women with endometriosis is determined by its localization, the age of the patient, ovarian reserve, the duration of infertility, the therapy and its effectiveness, the condition of the fallopian tubes, as well as spermogram parameters. The correctly chosen management strategy for this patient made it possible to achieve not only a clinical pregnancy, but also the birth of a healthy child.
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Reproductive outcomes of infiltrative endometriosis after surgical treatment with assisted reproductive technologies (a clinical case) - Authors: Trishkin A.G.1,2, Zotova O.A.1, Yushchenko M.A.3 - Affiliations: - Center for Family Health and Reproduction “Krasnaya Gorka” - Kemerovo State University - Kuzbass State Clinical Hospital named after S.V. Belyaev - Issue: Vol 20, No 1 (2024) - Pages: 139-142 - Section: GYNECOLOGY. CLINICAL CASE - Published: 18.05.2024 - URL: https://ojrs.abvpress.ru/ojrs/article/view/1219 - DOI: https://doi.org/10.17650/1994-4098-2024-20-1-139-142 - ID: 1219 Cite item Full Text Abstract Endometriosis is one of the most urgent problems of modern gynecology and reproductive medicine. About 40 % of women suffering from endometriosis of various localization are infertile. The use of drug therapy has not been proven to increase fertility. Currently, there is no consensus on the impact of surgical treatment on the effectiveness of assisted reproductive technologies. This article presents a clinical case of modern approache to the use of assisted reproductive technologies for endometriosis-associated infertility. The tactics of managing women with endometriosis is determined by its localization, the age of the patient, ovarian reserve, the duration of infertility, the therapy and its effectiveness, the condition of the fallopian tubes, as well as spermogram parameters. The correctly chosen management strategy for this patient made it possible to achieve not only a clinical pregnancy, but also the birth of a healthy child. About the authors A. G. Trishkin Center for Family Health and Reproduction “Krasnaya Gorka”;Kemerovo State University ORCID iD: 0009-0009-6012-7445 3a Suvorova St., 650044 Kemerovo, Russia 6 Krasnaya St., 650000 Kemerovo, Russia Russian FederationO. A. Zotova Center for Family Health and Reproduction “Krasnaya Gorka” Author for correspondence. Email: [email protected] ORCID iD: 0000-0002-4991-5354 Olga Aleksandrovna Zotova 3a Suvorova St., 650044 Kemerovo, Russia Russian FederationM. A. Yushchenko Kuzbass State Clinical Hospital named after S.V. Belyaev 22 Oktyabrskiy Prospekt, 650066 Kemerovo, Russia Russian FederationReferences - Pivazyan L.G., Unanyan A.L., Poymanova O.F. et al. Endometrioma: ovarian reserve and management. Problemy reproduktsii = Russian Journal of Human Reproduction 2021;27(5):77–83. (In Russ.). - Rusina E.I., Yarmolinskaya M.I., Piankova V.O. Deep infiltrative endometriosis. Contentious issues: pros and cons. Ginekologiya = Gynecology 2020;22(5):50–6. (In Russ.). doi: 10.26442/20795696.2020.5.200274 - Dunselman G.A., Vermeulen N., Becker C. et al. ESHRE guideline: Management of women with endometriosis. Hum Reprod 2014;29:400–12. doi: 10.1093/humrep/det457 - Kodaman P. Current strategies for endometriosis management. Obstet Gynecol Clin North Am 2015;42(1):87–101. doi: 10.1016/j.ogc.2014.10.005

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