Endometriose

In: Therapiehandbuch Gynäkologie und Geburtshilfe · 2020 · pp. 275–282 · doi:10.1007/978-3-662-59809-2_20 · W4229832791
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Endometriosis is a benign condition where uterine lining tissue grows outside the uterus, affecting 5-10% of women and potentially causing painful periods and infertility.

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The paper chapter describes endometriosis as a benign condition in which uterine endometrial tissue occurs outside the uterine cavity, noting that definitive diagnosis is invasive and that prevalence therefore remains uncertain; it estimates that about 5–10% of women of reproductive age have treatable disease. It outlines that the etiology is unclear but that displacement/spreading of uterine endometrium is considered important, and it highlights dysmenorrhea as the key symptom while also noting an association with infertility. A major limitation explicitly acknowledged is the uncertainty of prevalence due to the need for invasive confirmation. This paper is centrally about endometriosis — it defines the disease, summarizes presumed causes, symptomatology, and discusses diagnostic and epidemiologic uncertainty in endometriosis.

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Zusammenfassung Endometriose ist eine gutartige Erkrankung, definiert als das Auftreten von Gebärmutterschleimhaut außerhalb der Gebärmutterhöhle. Da die Erkrankung nur invasiv definitiv diagnostiziert werden kann, ist die genaue Prävalenz unklar; man schätzt, dass 5‒10 % der Frauen im gebärfähigen Alter eine behandlungsbedürftige Endometriose aufweisen. Die genaue Ursache ist ebenfalls unklar, wahrscheinlich spielt die Verschleppung von uterinem Endometrium eine wichtige Rolle. Das Leitsymptom ist die Dysmenorrhö, die Krankheit ist aber auch mit Sterilität assoziiert. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others Literatur American Society for Reproductive Medicine (1997) Revised American Society for Reproductive Medicine classification of endometriosis: 1996. Fertil Steril 67:817–821 Bendifallah S, Roman H, Mathieu d’Argent E, Touleimat S, Cohen J, Darai E, Ballester M (2017) Colorectal endometriosis-associated infertility: should surgery precede ART? Fertil Steril 108(3):525–553 Strowitzki T, Marr J, Gerlinger C, Faustmann T, Seitz C (2010) Dienogest is as effective as leuprolide acetate in treating the painful symptoms of endometriosis: a 24-week, randomized, multicentre, open-label trial. Hum Reprod 3:633–641 The ESHRE Capri Workshop Group (2008) Intrauterine devices and intrauterine systems. Hum Reprod Update 14(3):197–208 Weiterführende Literatur Abbott JA, Hawe J, Clayton RD, Garry R (2003) The effects and effectiveness of laparoscopic excision of endometriosis: a prospective study with 2‒5 year follow-up. Hum Reprod 18(9):1922–1927 Alborzi S, Momtahan M, Parsanezhad ME, Dehbashi S, Zolghadri J, Alborzi S (2004) A prospective, randomized study comparing laparoscopic ovarian cystectomy versus fenestration and coagulation in patients with endometriomas. Fertil Steril 82:1633–1637 Bianchi PH, Pereira RM, Zanatta A, Alegretti JR, Motta EL, Serafini PC (2009) Extensive excision of deep infiltrative endometriosis before in vitro fertilization significantly improves pregnancy rates. J Minim Invasive Gynecol 16(2):174–180 Clinical Green Top Guidelines. The investigation and management of endometriosis. http://www.rcog.org.uk, 23. Oktober 2006 Daraï E, Carbonnel M, Dubernard G et al (2010) Determinant factors of fertility outcomes after laparoscopic colorectal resection for endometriosis. 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Cochrane Database Syst Rev Issue 2:CD004992. https://doi.org/10.1002/14651858.cd004992.pub3 Hornstein MD, Yuzpe AA, Burry KA, Heinrichs LR, Buttram VL Jr, Orwoll ES (1995) Prospective randomized doubleblind trial of 3 versus 6 months of nafarelin therapy for endometriosis-associated pelvic pain. Fertil Steril 63:955–962 Hughes E, Brown J, Collins JJ, Farquhar C, Fedorkow DM, Vanderkerchove P (2007) Ovulation suppression for endometriosis for women with subfertility. Cochrane Database Syst Rev Issue 3:CD000155. https://doi.org/10.1002/14651858.cd000155.pub2 Jacobson TZ, Duffy JMN, Barlow D, Farquhar C, Koninckx PR, Olive D (2010) Laparoscopic surgery for subfertility associated with endometriosis. Cochrane Database Syst Rev Issue 1:CD001398. https://doi.org/10.1002/14651858.cd001398.pub2 Keckstein J, Ulrich U, Possover M, Schweppe KW (2003) ENZIAN-Klassifikation der tief infiltrierenden Endometriose. Zentralbl Gynäkol 125:291 Moore J, Copley S, Morris J, Lindsell D, Golding S, Kennedy S (2002) A systematic review of the accuracy of ultrasound in the diagnosis of endometriosis. Ultrasound Obstet Gynecol 20:630–634 Petta CA, Ferriani RA, Abrao MS et al (2005) Randomized clinical trial of a levonorgestrel-releasing intrauterine system and a depot GnRH analogue for the treatment of chronic pelvic pain in women with endometriosis. Hum Reprod 20(7):1993–1998 Sillem M (2015) Endometriose-Operationen: Wann? Warum? Wie? FRAUENARZT 56(4):330–334 Sillem M (2017) Medikamentöse Therapie der Endometriose – Aktueller Stand und Ausblick. Gynäkologische Praxis 42:5–10 Stepniewska A, Pomini P, Bruni F, Mereu L, Ruffo G, Ceccaroni M, Scioscia M, Guerriero M, Minelli L (2009) Laparoscopic treatment of bowel endometriosis in infertile women. Hum Reprod 24(7):1619–1625 Surrey ES (1999) Add-back therapy and gonadotropin-releasing hormone agonists in the treatment of patients with endometriosis: can a consensus be reached? Add-Back Consensus Working Group. Fertil Steril 71(3):420‒424 (Review) Sutton CJG, Pooley S, Ewen SP, Haines P (1997) Follow-up report on a randomized controlled trial of laser laparoscopy in the treatment of pelvic pain associated with mild to moderate endometriosis. Fertil Steril 68(6):1070–1074 Tuttlies F, Keckstein J, Ulrich U, Possover M, Schweppe KW, Wustlich M, Buchweitz O, Greb R, Kandolf O, Mangold R, Masetti W, Neis K, Rauter G, Reeka N, Richter O, Schindler AE, Sillem M, Terruhn V, Tinneberg HR (2005) ENZIAN-score, a classification of deep infiltrating endometriosis. Zentralbl Gynakol 127(5):275–281 Witz CA, Burns WN (2002) Endometriosis and infertility: is there a cause and effect relationship? Gynecol Obstet Invest 53(Suppl 1):2–11 Yap C, Furness S, Farquhar C, Rawal N (2004) Pre and post operative medical therapy for endometriosis surgery. Cochrane Database Syst Rev Issue 3:CD003678. https://doi.org/10.1002/14651858.cd003678.pub2 Author information Authors and Affiliations Corresponding author Editor information Editors and Affiliations Rights and permissions Copyright information © 2020 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature About this chapter Cite this chapter Sillem, M. (2020). Endometriose. In: Wacker, J., Sillem, M., Bastert, G., Beckmann, M. (eds) Therapiehandbuch Gynäkologie und Geburtshilfe. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-59809-2_20 Download citation DOI: https://doi.org/10.1007/978-3-662-59809-2_20 Published: Publisher Name: Springer, Berlin, Heidelberg Print ISBN: 978-3-662-59808-5 Online ISBN: 978-3-662-59809-2 eBook Packages: Medicine (German Language)

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