APPENDECTOMY

Nazeer Ahmed Pathan, Abdul Aziz Shaikh, Manzoor Ali Shaikh
In: The Professional Medical Journal · 2018 · vol. 25(09) , pp. 1301–1305 · doi:10.29309/tpmj/2018.25.09.51 · W3199203138
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Histopathological examination of 300 appendectomy specimens revealed endometriosis among other unusual incidental findings, highlighting the importance of routine analysis for proper diagnosis.

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This observational study investigated unusual incidental histopathological findings in 300 appendectomy specimens collected between January 2014 and March 2016. The researchers analyzed tissue sections stained with hematoxylin and eosin, identifying acute appendicitis in 57.66% of cases alongside rare conditions such as adenocarcinoma, carcinoid tumors, Crohn's disease, and parasitic infection. The male-to-female ratio was significantly skewed at 3.61:1, with a mean patient age of 19.5 years. The authors concluded that routine histopathological examination is essential for detecting these unexpected diagnoses to ensure appropriate clinical management. Relevance to endometriosis: listed as one of the unusual incidental findings identified in appendix specimens, though the paper's main focus is general histopathological screening rather than gynecological pathology.

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Abstract

Objectives: Investigating unusual incidental findings in appendectomyspecimens by histopathological examination. Study Design: Observational study. Place &Duration: Department of Pathology, Liaquat University of Medical and Health Sciences fromJanuary 2014 to March 2016. Subjects & Methods: 300 appendectomy specimens wereinvestigated. Biodata of patients on Pathological proforma and specimens was noted. 3- 5 μtissue sections of appendectomy were stained with H & Eosin stain for microscopy. Data wasanalyzed on SPSS version 22.0 (USA) at 95% CI (P ≤ 0.05). Results: Male to female ratiowas 3.61:1 (P=0.0001). Mean (± SD) age was 19.5±5.7 years. Acute appendicitis was notedin 57.66% of specimens. Unusual histopathological findings noted were adenocarcinoma,endometriosis, Crohn`s disease, carcinoid tumors and Enterobius vermicularis. Conclusion:Unusual incidental findings emphasize the importance of histopathological examination ofappendectomy specimen for proper diagnosis and timely intervention.
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APPENDECTOMY UNUSUAL INCIDENTAL HISTOPATHOLOGICAL FINDINGS IN APPENDECTOMY SPECIMENS DOI: https://doi.org/10.29309/TPMJ/2018.25.09.51Keywords: Appendectomy, Histopathology, Adenocarcinoma, Endometriosis, Crohn`s DiseaseAbstract Objectives: Investigating unusual incidental findings in appendectomy specimens by histopathological examination. Study Design: Observational study. Place & Duration: Department of Pathology, Liaquat University of Medical and Health Sciences from January 2014 to March 2016. Subjects & Methods: 300 appendectomy specimens were investigated. Biodata of patients on Pathological proforma and specimens was noted. 3- 5 μ tissue sections of appendectomy were stained with H & Eosin stain for microscopy. Data was analyzed on SPSS version 22.0 (USA) at 95% CI (P ≤ 0.05). Results: Male to female ratio was 3.61:1 (P=0.0001). Mean (± SD) age was 19.5±5.7 years. Acute appendicitis was noted in 57.66% of specimens. Unusual histopathological findings noted were adenocarcinoma, endometriosis, Crohn`s disease, carcinoid tumors and Enterobius vermicularis. Conclusion: Unusual incidental findings emphasize the importance of histopathological examination of appendectomy specimen for proper diagnosis and timely intervention.

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