Diameter of dominant leiomyoma is a possible determinant to predict coexistent endometriosis

Isono W, Wataru Isono, Osamu Wada‐Hiraike, Osamu Wada-Hiraike, Yutaka Osuga, Osuga Y, Tetsu Yano, Yano T, Yuji Taketani, Taketani Y
European journal of obstetrics, gynecology, and reproductive biology · 2012 · vol. 162(1) , pp. 87–90 · doi:10.1016/j.ejogrb.2012.01.018 · PMID:22377227 · W2056178484
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This study found that a dominant leiomyoma diameter less than 8 cm was a significant predictor of coexistent endometriosis in patients undergoing surgery for uterine leiomyomas.

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Abstract

ObjectiveTo identify the frequency and assess risk factors for unexpected discovery of peritoneal endometriotic implants in patients who underwent myomectomy or hysterectomy for symptomatic uterine leiomyomas.Study designWe retrospectively collected medical records of 829 patients with symptomatic leiomyomas in The University of Tokyo Hospital. All the patients underwent abdominal or laparoscopic surgeries between January 2001 and December 2010 and the presence or absence of endometriosis during surgery was analyzed. Possible determinant to predict coexistent endometriosis was statistically investigated.ResultsIn total, 105 leiomyoma cases (12.7% in 829 patients) were diagnosed with endometriosis. Patients with small dominant leiomyomas were significantly complicated by peritoneal endometriotic implants (small leiomyomas were classified as < 8 cm). The patients with both diagnoses were more likely to be infertile and at age 39 years or younger than those with leiomyoma alone.ConclusionsWomen undergoing myomectomy or hysterectomy with both endometriosis and leiomyomas have several different clinical features compared with women with only leiomyomas. The size of largest leiomyoma may provide an important clue for coexistent endometriosis. Women with substantial infertility despite a smaller leiomyomas burden may be more likely to have a surgical indication for concomitant endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Leiomyomatosis Peritoneal Diseases Uterine Neoplasms Adult Endometriosis Female Humans Laparoscopy Leiomyomatosis Leiomyomatosis Middle Aged Peritoneal Diseases Predictive Value of Tests Retrospective Studies Uterine Neoplasms Uterine Neoplasms Uterus Uterus

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