Nerve growth factor (NGF) and NGF mRNA change in rat uterus during pregnancy

Füsun Varol, Anne‐Marie Duchemin, Norton H. Neff, Maria Hadjiconstantinou
In: Neuroscience Letters · 2000 · vol. 294(1) , pp. 58–62 · doi:10.1016/s0304-3940(00)01533-0 · PMID:11044586 · W2052218259
article OA: closed CC0 ⤵ 4 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-12 ⓘ

Nerve growth factor (NGF) and its messenger RNA (mRNA) levels were analyzed in the rat uterus throughout pregnancy to understand their role in uterine physiology.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

During pregnancy, the uterus undergoes a profound sympathetic denervation. To explore whether this is associated with changes in neurotrophic factors, we assayed nerve growth factor (NGF) and NGF mRNA in the uterus of non-pregnant and pregnant rats. In the uterine horn, the concentration of NGF and its mRNA decreased during middle and late pregnancy. However, when values were corrected for the increase of uterine weight and total RNA yield during pregnancy, NGF content and mRNA per horn increased during middle and late pregnancy. Similar, but less pronounced, changes were observed in the cervix. By seven days postpartum, both parameters returned to near normal.

My notes (saved in your browser only)

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cited by (4)

References (25)

Cited by (4)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK