Severe hemoperitoneum due to endometriosis in a non-pregnant woman under dienogest therapy: a case report
Case report
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This report details a severe hemoperitoneum in a non-pregnant woman with endometriosis on dienogest therapy, which was successfully treated via laparoscopy to achieve hemostasis.
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Abstract
Endometriosis is a chronic, estrogen-dependent, inflammatory disease that mainly affects women of reproductive age and is defined by the presence of endometrial glands and stroma at ectopic sites. Spontaneous hemoperitoneum due to bleeding of pelvic endometriotic foci represents a very rare and severe complication of endometriosis, although most cases described in literature regard pregnant women. We hereby present a case of a severe hemoperitoneum in a non-pregnant, 42 years old woman, under dienogest therapy for deep endometriosis. This life-threatening condition was promptly managed by performing an exploratory laparoscopy where the source of bleeding was found and hemostasis successfully achieved.Bleeding from pelvic endometriotic foci ought to be considered in the differential diagnosis of gynecological causes of acute abdomen and hemoperitoneum, even under medical therapy.
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References (7)
- A very rare case of endometriosis presenting with massive hemoperitoneum via openalex
- Clinical diagnosis of endometriosis and optimal medical therapy via openalex
- Efficacy and Safety of Long-Term Use of Dienogest in Women With Ovarian Endometrioma via openalex
- Massive haemoperitoneum from endometriosis masquerading as ruptured ectopic pregnancy: case report via openalex
- Spontaneous hemoperitoneum in pregnancy (SHiP) and endometriosis - A systematic review of the recent literature via openalex
- W2412266915 via openalex
- doi:10.1055/s-0029-1210402 via openalex
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- europepmc
- last seen: 2026-10-16T06:09:50.462052+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
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- unpaywall
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