Endometriose – Update 2016
This review synthesizes current knowledge on endometriosis, covering its pathophysiology, medical and surgical treatment options, impact on fertility and pregnancy, and potential precancerous nature.
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This 2016 update paper discusses endometriosis as the most common gynecological disease, emphasizing the clinical challenge posed by its pleiotropic symptoms, complexity, and difficult-to-prognosticate consequences such as chronic pain and long-term involuntary infertility. It provides a structured overview of current thinking on diagnosis and differentiating workup, and raises key decision points regarding when medical therapy is appropriate versus when surgery is considered, how to manage recurrence, and how fertility treatment should be handled, noting that serious decisions require transdisciplinary input and certified endometriosis centers. It also includes expert perspectives on the latest pathophysiology (including the question of causal therapy), medication options, whether complete eradication of lesions remains a standard surgical approach, pregnancy outcomes, and whether endometriosis might be a precancerous condition. The paper does not present absolute answers or definitive solutions, framing itself as an expert synthesis meant to generate further questions, which relates centrally to endometriosis. This paper is centrally about endometriosis — it serves as a 2016 expert update covering diagnosis, pathophysiology, treatment options, surgical strategy, and pregnancy and potential precancer risk.
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