Pseudo-invasive Vasculocentric Adenomyosis- A Diagnostic Dilemma

Kafil Akhtar, Andleeb Abrari, Rachel Tirkey
In: Asian Pacific Journal of Cancer Biology · 2023 · vol. 8(4) , pp. 403–405 · doi:10.31557/apjcb.2023.8.4.403-405 · W4390117185
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⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This paper describes a rare case of pseudo-invasive, vasculocentric adenomyosis in a 47-year-old woman, a benign uterine lesion diagnosed microscopically, presenting with pelvic pain and abnormal bleeding.

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This paper describes a rare diagnostic dilemma case of pseudo-invasive, vasculocentric adenomyosis in a 47-year-old multiparous woman with chronic pelvic pain, menorrhagia, dyspareunia, and excessive menstrual bleeding, with a prior lower uterine cesarean section 10 years earlier. It characterizes the lesion as benign and defined microscopically by variable-sized non-neoplastic endometrial glands surrounded by endometrial stroma located deep within uterine myometrial blood vessels. The paper notes that such cases are typically seen in multiparous women in their fourth and fifth decades and may present with abnormal bleeding, pelvic pain, dysmenorrhea, dyspareunia, or infertility, though about a third can be asymptomatic. It states that microscopic examination of hysterectomy specimens remains the gold standard for definitive diagnosis. This paper is centrally about adenomyosis—specifically pseudo-invasive, vasculocentric adenomyosis presenting as a rare benign lesion within uterine vasculature.

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Abstract

Pseudo-invasive, vasculocentric adenomyosis is a rare benign lesion of the uterus, characterized by the aberrant, pathological presence of variable sized, non-neoplastic endometrial glands and surrounded by endometrial stroma deep within the myometrial blood vessels. This condition usually affects multiparous women in their fourth and fifth decades, with other risk factors being prior caesarian surgery or uterine surgery. Mostly the patients present with abnormal uterine bleeding, pelvic pain, dysmenorrhea, dyspareunia, or infertility while a third of them may be asymptomatic. Microscopic examination of hysterectomy specimens remains the gold standard to make a definitive diagnosis. Herein we present a rare case of Pseudo-invasive, vasculocentric Adenomyosis in a 47 year old multigravida female, who presented with a history of chronic pelvic pain with menorrhagia, dyspareunia and excessive menstrual bleeding for the past four months, with a history of lower uterine caesarean section a decade ago.
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Pseudo-invasive Vasculocentric Adenomyosis- A Diagnostic Dilemma DOI: https://doi.org/10.31557/apjcb.2023.8.4.403-405Keywords: Adenomyosis, Immunohistochemistry, Pseudo-invasive, Vasculocentric, Uterus.Abstract Pseudo-invasive, vasculocentric adenomyosis is a rare benign lesion of the uterus, characterized by the aberrant, pathological presence of variable sized, non-neoplastic endometrial glands and surrounded by endometrial stroma deep within the myometrial blood vessels. This condition usually affects multiparous women in their fourth and fifth decades, with other risk factors being prior caesarian surgery or uterine surgery. Mostly the patients present with abnormal uterine bleeding, pelvic pain, dysmenorrhea, dyspareunia, or infertility while a third of them may be asymptomatic. Microscopic examination of hysterectomy specimens remains the gold standard to make a definitive diagnosis. Herein we present a rare case of Pseudo-invasive, vasculocentric Adenomyosis in a 47 year old multigravida female, who presented with a history of chronic pelvic pain with menorrhagia, dyspareunia and excessive menstrual bleeding for the past four months, with a history of lower uterine caesarean section a decade ago. Downloads Published How to Cite Issue Section License West Asia Organization for Cabcer Prevention retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License 4 (This permits anyone to copy, distribute, transmit and adapt the published work, provided the original work and source are appropriately cited).

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Condition tags

adenomyosischronic_pelvic_paindysmenorrheadyspareuniainfertility

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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