Current status of integral medical study on endometriosis

Chaoqin Yu, Jin Yu
In: Chinese Journal of Integrative Medicine · 2003 · vol. 9(2) , pp. 153–156 · doi:10.1007/bf02838579 · W2025923161
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-13 ⓘ

This review consolidates studies on traditional Chinese medicine treatments for endometriosis, including herbal granules, decoctions, and therapies targeting endocrine hormones, cytokines, and inflammatory mediators.

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This paper is a brief review titled “Current status of integral medical study on endometriosis” that surveys published studies of “integral” (integrative/traditional Chinese medicine and related biomedical investigations) approaches for endometriosis. It highlights a range of reports including clinical observations using TCM therapies aimed at resolving stasis, phlegm, and nodules, and experimental work examining endocrine and cytokine-related outcomes such as serum hormones, interleukins, and VEGF mRNA, as well as mechanistic findings involving complement component 3 in endometriotic tissue. The limitation is that, as a status review, it compiles heterogeneous studies rather than providing new pooled analyses or standardized comparative results. This paper is centrally about endometriosis — it summarizes the current body of integrative medical research including both TCM treatment reports and associated biomarker/experimental studies.

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References WANG M, LIN YH. Endometriosis treated by Fukang Granule and androgen. Zhejiang J TCM 1991; 1(1): 21 -23. XU LF, HAN B, LI TX. Experimental study on effect of soften hardness to dissipate nodule method with Futongning on neuro-endocrine system in patients with endometriosis. Tianjin J TCM 2002; 19(1): 61–62. YANG HY, OUYANG HQ, LUO SP, et al. Effect of Chinese herbal medicine on serum endocrine hormones and their receptors in experimental endometriosis. New J TCM 2001; 33(6): 75–77. LIU JX, MAO SX, ZHANG YC. Clinical study on treatment of endometriosis with TCM therapy for dissolving stasis, removing phlegm, softening hardness to dissipate nodule. Chin J Integr Tradi West Med 1994; 24 (6): 337–339. ZHOU YR, SUN FL, LIU AM. Clinical observation on treatment of 60 patients with endometriosis with TCM therapy for separating and dissipating stasis and phlegm. New J TCM 1999;31(1): 19–20. WU F. Treatment of 53 patients of endometriosis by TCM therapy depending Syndrome Differentiation. Liaoning J TCM 1997; (3) : 122. SONG ZL, SHU LD. Clinical observation on treatment of endometriosis with method of clearing Heat and activating blood circulation. Hubei J TCM 2000; 22(11): 12–14. WANG HZ. Treatment of endometriosis with Vervain. J TCM 2000; 42(6): 331. YING Y. Treatment of endometriosis with Huamo decoction. J Zhejiang College of TCM 1998; 22(2): 23–24. YU CQ, LIU YH, CAI ZL. Levels of interleukin-8 and -10 in patients with endometriosis and effect of Neiyi recipe on them. Chin J Integr Tradi West Med 2000; 20 (8): 603–605. YU CQ, CAI ZL, LIU YH, et al. Effect of Neiyi recipe on cytokines and VEGF mRNA expression in patients with endometriosis. J Anhui TCM Univ 2002; 21(6): 36–39. LIU J, LI XY, HU XM. Clinical observation on treatment of endometriosis by nourishing Shen and removing stasis. Chin J Integr Tradi West Med 1998, 18(3): 145. ZHENG LX. Clinical study on treatment of endometriosis with nourishing Shen and removing stasis. J Nanjing University of TCM 2000; 16(5): 277–279. SU CZ, HOU JF, ZHOU Q. Observation on treatment of 80 patients with endometriosis by Dangui Zhuyu decoction. J Practical TCM 2002; 18(6): 3–4. Isaacson KB, Coutifaris C, Garcia C, et al. Production and secretion of complement component 3 by endometriotic tissue. J Clin Endocrinol Metab 1989; 69: 1003–1009. Isaacson KB, Xu Q, Lyttle CR. The effect of estradiol on the production and secretion of complement component 3 by the rat uterus and surgically induced endometriotic tissue. Fertil Steril 1991; 55: 395–402. Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Chao-qin, Y., Jin, Y. Current status of integral medical study on endometriosis. Chin. J. Integr. Med. 9, 153–156 (2003). https://doi.org/10.1007/BF02838579 Received: Issue date: DOI: https://doi.org/10.1007/BF02838579

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