[Carcinoma developing in extragonadal endometriosis--analysis of two cases].

Grzegorz Panek, Jan M. Zielinski, Jan Zieliński
Ginekologia polska · 2002 · vol. 73(5) , pp. 454–9 · PMID:12185707 · W2411604453
article OA: closed CC0 ⤵ 1 in-corpus citation
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Abstract

Two cases of invasive carcinoma developing in extragonadal endometriosis are presented. Each case had a different clinical course. In addition to routine histopathologic studies immunohistochemical studies to assess the expression of cytoceratin and glycoprotein CD-44 were performed. In both cases CK-7 expression was higher in malignancy then in the endometrioid tissue. Very high expression of CD-44 protein (marker of metastatic potential) was found in patients with poor progress of the disease.

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Condition tags

endometriosis

MeSH descriptors

Abdomen Abdomen Abdomen Carcinoma Endometriosis Perineum Perineum Perineum Skin Neoplasms Adult Biomarkers, Tumor Biomarkers, Tumor Carcinoma Carcinoma Carcinoma Cell Transformation, Neoplastic Cell Transformation, Neoplastic Endometriosis Endometriosis Female

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