Endometriosis: modern principles of diagnosis and treatment (literature review). Part 1. Therapy

In: Vestnik of Vitebsk State Medical University · 2019 · vol. 18(6) , pp. 16–22 · doi:10.22263/2312-4156.2019.6.16 · W2994860209
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AI-generated summary by claude@2026-06, 2026-06-08

This literature review outlines modern principles for diagnosing and treating endometriosis, focusing specifically on therapeutic approaches.

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AI-generated deep summary by claude@2026-06, 2026-06-10

This literature review analyzes and summarizes recommendations from international, European, and national professional societies, along with Cochrane systematic reviews, focusing on treatment strategies for endometriosis. Using authors’ hospital data, it also discusses the prevalence of endometriosis among patients and outlines key diagnostic principles, noting that diagnosis remains challenging and that no biochemical marker (including CA-125) is sufficiently accurate. The review reports a consensus shift toward conservative management, emphasizing that hormonal therapies are symptomatic rather than curative, that combined low-dose oral contraceptives and low-cost progestins should be first-line due to comparable efficacy and better tolerability, and that second-line options include add-back GnRH agonists, a levonorgestrel-releasing intrauterine system (with need for further research), depot progestins, and other regimens; it also highlights that recurrence of symptoms after stopping medication is common, requiring long-term/anti-relapse management under follow-up. This paper is centrally about endometriosis — it reviews modern principles of diagnosis and conservative and long-term therapeutic management, including relapse prevention.

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endometriosis

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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