An Asymptomatic Giant Endometrioma Presented as Lower Extremity Deep Vein Thrombosis with Early Pregnancy: A Case Report and Review of the Literature

Shweta Alok Sonthalia, Sonthalia SA, Junching Wong, Wong J, Agrawal SJ, Shalini Jain Agrawal
Journal of obstetrics and gynaecology of India · 2024 · vol. 75(S1) , pp. 619–622 · doi:10.1007/s13224-024-02058-5 · PMID:40390932 · PMC12085535 · W4403005693
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This case report details an instance of an asymptomatic giant endometrioma presenting as deep vein thrombosis in early pregnancy and reviews relevant literature.

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This case report describes a pregnant patient who presented with lower extremity deep vein thrombosis and was subsequently found to have an asymptomatic giant endometrioma. The authors review existing literature to highlight the rare association between large ovarian endometrial cysts and venous thromboembolic events, particularly during pregnancy when hypercoagulability is already elevated. They emphasize that even in the absence of typical pelvic symptoms, significant endometriotic lesions can contribute to systemic complications like DVT through mass effect or inflammatory mechanisms. This paper is centrally about endometriosis — specifically a giant endometrioma presenting as deep vein thrombosis in early pregnancy.

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References Yahya A, Mustapha A, Kolawole AO, et al. Giant ovarian endometrioma: a case report. J West Afr Coll Surg. 2021;11(4):41–4. https://doi.org/10.4103/jwas.jwas_40_21. Rafi J, Pathiraja PDM, Gelson E, et al. Obstetric and perinatal outcomes in women with endometriosis. ObstetGynecol. 2022;24(242):250. https://doi.org/10.1111/tog.12831. Sharma RP, Delly F, Marin H, et al. Endometriosis causing lower extremity deep vein thrombosis—case report and review of the literature. Int J Angiol. 2009;18(4):199–202. https://doi.org/10.1055/s-0031-127835. Ishikawa H, Taga M, Haruki A, et al. Huge ovarian endometrial cyst: a case report. Eur J Obstet Gynecol Reprod Biol. 1997;74:215–7. Funding None. Author information Authors and Affiliations Corresponding author Ethics declarations Conflict of interest There are no conflicts of interest. Additional information Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Shweta Alok Sonthalia is a Obstetrician and Gynaecologist; Junching Wong is a Obstetrician and Gynaecologist; and Shalini Jain Agrawal is a Obstetrician and Gynaecologist. Rights and permissions Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. About this article Cite this article Sonthalia, S.A., Wong, J. & Agrawal, S.J. An Asymptomatic Giant Endometrioma Presented as Lower Extremity Deep Vein Thrombosis with Early Pregnancy: A Case Report and Review of the Literature. J Obstet Gynecol India 75 (Suppl 1), 619–622 (2025). https://doi.org/10.1007/s13224-024-02058-5 Received: Accepted: Published: Version of record: Issue date: DOI: https://doi.org/10.1007/s13224-024-02058-5

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