Management of the painful and nodular breast

C A Gateley, C. Gateley, R E Mansel
British medical bulletin · 1991 · vol. 47(2) , pp. 284–294 · doi:10.1093/oxfordjournals.bmb.a072470 · PMID:1834299 · W1900475422
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Drug treatment for breast pain and nodularity is considered only for severe symptoms, with danazol, bromocriptine, or evening primrose oil showing efficacy in mastalgia, and benign nodularity generally not requiring surgical biopsy.

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Abstract

Mild breast pain and nodularity are common and may be considered normal. Only when symptoms are severe enough to affect the patient's lifestyle should drug treatment be considered. Using danazol, bromocriptine or evening primrose oil a clinically useful improvement in pain can be anticipated in 77% of patients with cyclical mastalgia and 44% with non-cyclical mastalgia. Benign nodularity should not be biopsied surgically as it is unnecessary and makes subsequent assessment of the breast difficult.

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MeSH descriptors

Breast Diseases Pain Adult Age Factors Breast Diseases Breast Diseases Bromocriptine Bromocriptine Buserelin Buserelin Buserelin Danazol Danazol Estrogen Replacement Therapy Fatty Acids, Essential Fatty Acids, Essential Female gamma-Linolenic Acid Goserelin Humans

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