Effectiveness of microlaparoscopy in the diagnosis of premature ovarian failure

Noriko Abe, Hiroyuki Takeuchi, Iwaho Kikuchi, Katsuyuki Kinoshita
In: Journal of Obstetrics and Gynaecology Research · 2006 · vol. 32(2) , pp. 224–229 · doi:10.1111/j.1447-0756.2006.00375.x · PMID:16594929 · W1858378765
article OA: closed CC0
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-08-01 ⓘ

Microlaparoscopy effectively differentiated between type A and B premature ovarian failure by examining ovarian morphology, which correlated with antinuclear antibody positivity and follicle presence.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

AIM: Premature ovarian failure (POF) cases contain a mixture of cases possessing follicles (type A) and those depleted of follicles (type B). Differentiation between the two types is important because the treatment policy and pregnancy prognosis vary greatly. The objective of this study was to examine the usefulness of microlaparoscopy in the differentiation of types A and B. METHODS: Among 66 patient with POF diagnosed at our department between May 1996 and April 2004, 47 patients who gave informed consent and underwent microlaparoscopy were studied. The cases were divided into four groups based on the laparoscopic ovarian morphology. These groups were analyzed with respect to patient background, blood hormone levels, antinuclear antibody positive rate, visualization of the ovary on transvaginal ultrasonography, presence or absence of follicles in biopsy specimen, and number of follicles. RESULT: No significant differences in patient background and serum hormone levels were observed between groups. There was a tendency of increase in antinuclear antibody positive rate, increase in proportion of cases with follicles, and increase in number of follicles as the ovarian morphology approached normal. Transvaginal ultrasonography failed to identify the ovary in all the patients. CONCLUSION: Microlaparoscopy is useful in the differentiation between type A and B POF, and is further expected to become an indicator of response to treatment.

My notes (saved in your browser only)

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cites (1)

References (21)

Source provenance

openalex
last seen: 2026-05-11T06:38:17.545654+00:00
unpaywall
last seen: 2026-10-06T06:46:56.404536+00:00
License: CC0 · commercial use OK