Resolution of pelvic pain related to adenomyosis following treatment with dextroamphetamine sulfate

Check JH, J H Check, A. Jaffe, Jaffe A
Clinical and experimental obstetrics & gynecology · 2015 · vol. 42(5) , pp. 671–672 · doi:10.12891/ceog2104.2015 · PMID:26524821 · W2432832454
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This paper reports a single-patient clinical case in which a 32-year-old woman with daily severe chronic pelvic pain attributed to adenomyosis (diagnosed by MRI) received dextroamphetamine sulfate after laparoscopic removal of endometriosis plus treatment with oral contraceptives and ibuprofen did not relieve the pain. The authors report that within three months the pelvic pain was completely resolved and remained absent for six months. The main limitation is that it is an individual case report with no control group, so causality cannot be established. This paper is centrally about adenomyosis — it describes resolution of adenomyosis-related pelvic pain after dextroamphetamine sulfate treatment.

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Abstract

PURPOSE: To determine if treatment with dextroamphetamine sulfate can reduce pelvic pain that was attributed to adenomyosis. MATERIALS AND METHODS: Dextroamphetamine sulfate was given to a 32-year-old woman who suffered on a daily basis from severe chronic pelvic pain that was not relieved by laparoscopic removal of endometriosis by oral contraceptive and ibuprofen. The adenomyosis was diagnosed by magnetic resonance imaging. RESULTS: Within three months the pain was completely gone and has remained absent for six months. CONCLUSIONS: Dextroamphetamine sulfate relieved pain from adenomyosis similar to its effect on endometriosis.
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Abstract

Purpose: To determine if treatment with dextroamphetamine sulfate can reduce pelvic pain that was attributed to adenomyosis. Materials and Methods: Dextroamphetamine sulfate was given to a 32-year-old woman who suffered on a daily basis from severe chronic pelvic pain that was not relieved by laparoscopic removal of endometriosis by oral contraceptive and ibuprofen. The adenomyosis was diagnosed by magnetic resonance imaging. Results: Within three months the pain was completely gone and has remained absent for six months. Conclusions: Dextroamphetamine sulfate relieved pain from adenomyosis similar to its effect on endometriosis.

Keywords

- Adenomyosis - Chronic pelvic pain - Dextroamphetamine sulfate - Endometriosis - Sympathetic hypofunction

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Condition tags

chronic_pelvic_painendometriosisadenomyosis

MeSH descriptors

Adenomyosis Central Nervous System Stimulants Dextroamphetamine Pelvic Pain Adenomyosis Adenomyosis Adenomyosis Adult Central Nervous System Stimulants Chronic Pain Dextroamphetamine Female Humans Magnetic Resonance Imaging Pelvic Pain Pelvic Pain

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