Участие свободнорадикальных процессов в возможных механизмах развития сонета иных гиперпластических процессов органов репродуктивной системы женщин

•·Intact myometrium specimen, received from 56 •women of reproductive age during surgical interventions. There •were 30 women with combined hyperplastic processes in the •reproductive system organs (uterine myoma, endometrium hy•perplasia, adenomyosis, benign ovarian tumors, mastopathy, •background cervical pathology), and in 26 cases solitary uterine •myoma was found. At infrared spectrometry of the lyofilized •myometrium, taken from patients with combined proliferation •foci, a stable peak with wave number 3500 snr1 was found, which •reflects the accumulation of molecules with oxidized OH-groups •and a change in proportion of OH-/NH-containing molecules. •At the study of the myometrium of patients with single myoma •focus the described peak was absent. The acquired data sug •gests, that combined benign hyperplasias in the reproductive •system organs are accompanied by the oxidative stress cascade •reactions, characterized by uncontrollable production of free •radicals and/or insufficiency of antiradical protection mecha •nisms. •