Pain Self-Efficacy, Pain Acceptance and Quality of Life in Endometriosis

Lisa Pye, David Sheffield
In: Women's Reproductive Health · 2026 · pp. 1–14 · doi:10.1080/23293691.2026.2709003 · W7203484398
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Analysis of 468 individuals with endometriosis demonstrated that pain self-efficacy and chronic pain acceptance significantly associate with quality of life, particularly explaining greater variance in pain-related outcomes than overall health.

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Abstract

Research associates pain self-efficacy (PSE) and chronic pain acceptance (CPA) with quality of life (QoL). This study explored this in endometriosis. Data from online self-report questionnaires from people (N = 468) with endometriosis with or without comorbidities were analyzed using hierarchical multiple regression. PSE and CPA both associated with QoL. Those with comorbidities reported greater pain and lower QoL, but interactions with PSE and CPA did not significantly increase variance explained. PSE and CPA explained greater variance in associations with pain-related QoL than overall health-related QoL. This suggests PSE and CPA associate with QoL in endometriosis.

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