[Tumor necrosis factor in peritoneal fluid of infertile women with endometriosis and its relation to sperm motility].
article
OA: closed
CC0
⤵ 6 in-corpus citations
AI-generated summary
Tumor necrosis factor levels were significantly higher in infertile women with endometriosis and negatively correlated with sperm motility and membrane integrity.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
Tumor necrosis factor (TNF) of 16 infertile women with endometriosis was measured in their peritoneal fluid (PF) with double monoclonal antibody ELISA method, and its effect on sperm motility and membrane integrity was evaluated by semen analysis and hypoosmotic swelling test (HOS). Comparing with that of infertile women without endometriosis (n = 11) and normal fertile women (n = 7), the level of PF-TNF was significantly higher in women with endometriosis (P < 0.01), in accord with the stage of the disease. In the PF of these patients after incubation with the donor sperms, the percentages of forward movement, total motility and hypoosmotic swelling of the donor sperms were significantly decreased (P < 0.01), showing a negative correlation to TNF levels. These results indicate that the elevation of PF-TNF in endometriosis has detrimental effect on sperm function.
My notes (saved in your browser only)
Condition tags
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
Cited by (6)
- Baboon Model for the Study of Endometriosis 2007
- The Baboon as an Appropriate Model for the Study of Multifactoral Aspects of Human Endometriosis 2005
- Endometriosis is sustained by tumour necrosis factor-α 2002
- Endometriosis-associated infertility 1997
- Peritoneal Cellular Immunity and Endometriosis 1997
- Spontaneous and induced synthesis of cytokines by peripheral blood monocytes in patients with endometriosis 1996
Source provenance
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0
· commercial use OK