Role of interventional pain management in patients with chronic pelvic pain

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Superior hypogastric plexus blocks successfully treated a 51-year-old woman's chronic pelvic pain caused by endometriosis, highlighting interventional pain management's role.

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This case report describes a 51-year-old woman with chronic pelvic pain secondary to endometriosis who experienced significant relief after receiving bilateral superior hypogastric plexus blocks. Despite undergoing multiple surgeries and high-dose opioid therapy that failed to control her symptoms, the interventional pain procedure provided approximately 70% to 80% pain relief lasting four months per injection. The authors note that while the patient’s diagnosis was confirmed via laparoscopy, surgical intervention alone did resolve her pain, highlighting the utility of nerve blocks for sympathetically mediated pain in this context. This paper is centrally about endometriosis — specifically as the underlying cause of chronic pelvic pain treated with superior hypogastric plexus blockade.

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Abstract

Patients with chronic pelvic pain are often referred to a variety of specialists in gynecology, urology, and gastroenterology with the hope of finding a diagnosis and treatment. We describe a 51-year-old woman with long-standing chronic pelvic pain secondary to endometriosis who was successfully treated with superior hypogastric plexus blocks. Physicians should consider referring patients to interventional pain specialists for assistance with pain control after thorough diagnostic evaluation.
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Abstract

Patients with chronic pelvic pain are often referred to a variety of specialists in gynecology, urology, and gastroenterology with the hope of finding a diagnosis and treatment. We describe a 51-year-old woman with long-standing chronic pelvic pain secondary to endometriosis who was successfully treated with superior hypogastric plexus blocks. Physicians should consider referring patients to interventional pain specialists for assistance with pain control after thorough diagnostic evaluation.

Keywords

Chronic pelvic, interventional pain management, pain, superior hypogastric plexus block pain Chronic pelvic pain (CPP) is generally defined as noncyclic pelvic pain lasting >3 to 6 months. It is a fairly common problem, affecting 6% to 26% of reproductive-age women.1,2 The most common problems leading to CPP are irritable bowel syndrome, adhesions, musculoskeletal causes, uterine disorders such as fibroids, and endometriosis. Patients with CPP may have multiple causes of pain, because endometriosis and interstitial cystitis commonly occur together.3 There is also a risk that continued pain will lead to central sensitization and the development of chronic pain.4 We present a case of a 51-year-old woman with long-standing CPP secondary to endometriosis who was successfully treated with superior hypogastric plexus blocks. CASE DESCRIPTION A 51-year-old woman had CPP in her lower abdomen and pelvic region, which she described as severe and cramping. She was managed by her primary care physician for the disorder for several years with conservative management including oral contraceptives and pain medications such as nonsteroidal anti-inflammatory drugs. She was referred to several specialists including gastroenterology, urology, and gynecology for further assistance with her condition. The patient underwent several invasive diagnostic tests and surgeries including laparoscopy, biopsies, and lysis of adhesions. She was diagnosed with endometriosis based on diagnostic laparoscopy and biopsies suggestive of the disease. These surgeries established the diagnosis but were unsuccessful in treating her CPP. She was started on stronger pain medications, including neuropathic agents and opioids. She was taking >90 morphine milligram equivalents, which is not recommended for the treatment of nonmalignant pain.5 After several years of struggling with this condition, the patient was referred to interventional pain management. A diagnostic and therapeutic bilateral superior hypogastric plexus block was performed under image guidance with the use of 8 mg of dexamethasone and 18 mL of 0.25% bupivacaine, divided equally for each side (Figure 1). The patient reported significant improvement shortly after the procedure was performed that lasted 4 months. She continues to receive repeat injections, with each injection providing 70% to 80% pain relief lasting approximately 4 months. She reported significant improvement in her pain scores and quality of life and was able to wean her opioid dose down to 15 morphine milligram equivalents with the addition of these pain procedures.

Discussion

CPP is often a difficult diagnostic and therapeutic dilemma, resulting in prolonged patient suffering. Physicians should be aware of additional treatment options for CPP before resorting to high-dose opioid therapy. Earlier referral to interventional pain physicians and consideration of superior hypogastric plexus blockade could provide effective treatment of sympathetically mediated CPP for some patients in this complex patient population.6,7

References

- 1.Grace VM, Zondervan KT. Chronic pelvic pain in New Zealand: prevalence, pain severity, diagnoses and use of the health services. Aust N Z J Public Health. 2004;28:369–375. doi: 10.1111/j.1467-842X.2004.tb00446.x. [DOI] [PubMed] [Google Scholar] - 2.Ahangari A. Prevalence of chronic pelvic pain among women: an updated review. Pain Physician. 2014;17:E141–E147. [PubMed] [Google Scholar] - 3.Tirlapur SA, Kuhrt K, Chaliha C, Ball E, Meads C, Khan KS. The “evil twin syndrome” in chronic pelvic pain: a systematic review of prevalence studies of bladder pain syndrome and endometriosis. Int J Surg. 2013;11:233–237. doi: 10.1016/j.ijsu.2013.02.003. [DOI] [PubMed] [Google Scholar] - 4.Stratton P, Khachikyan I, Sinaii N, Ortiz R, Shah J. Association of chronic pelvic pain and endometriosis with signs of sensitization and myofascial pain. Obstet Gynecol. 2015;125:719–728. doi: 10.1097/AOG.0000000000000663. [DOI] [PMC free article] [PubMed] [Google Scholar] - 5.Dowell D, Haegerich TM, Chou R. CDC guideline for prescribing opioids for chronic pain—United States, 2016. JAMA. 2016;315:1624–1645. doi: 10.1001/jama.2016.1464. [DOI] [PMC free article] [PubMed] [Google Scholar] - 6.Wechsler RJ, Maurer PM, Halpern EJ, Frank ED. Superior hypogastric plexus block for chronic pelvic pain in the presence of endometriosis: CT techniques and results. Radiology. 1995;196:103–106. doi: 10.1148/radiology.196.1.7784552. [DOI] [PubMed] [Google Scholar] - 7.Nagpal AS, Moody EL. Interventional management for pelvic pain. Phys Med Rehabil Clin N Am. 2017;28:621–646. doi: 10.1016/j.pmr.2017.03.011. [DOI] [PubMed] [Google Scholar]

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endometriosischronic_pelvic_pain

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