Deeply infiltrating endometriosis of the sigmoid and lymph nodes simulating obstructive neoplasm

In: Hellenic Journal of Surgery · 2010 · vol. 82(5) , pp. 337–341 · doi:10.1007/s13126-010-0053-3 · W2043583356
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This case report describes a 35-year-old patient with deeply infiltrating endometriosis of the sigmoid and lymph nodes that mimicked an obstructive neoplasm, requiring surgical resection for diagnosis and treatment.

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This paper reports a rare 35-year-old case of deeply infiltrating sigmoid endometriosis with regional lymph node involvement, presenting with 12 months of abdominal pain and diarrhoea with catamenial worsening. The authors used clinical and laboratory evaluation, CT and colonoscopy (showing eccentric sigmoid wall thickening and extensive stenosis covered by normal mucosa), and found elevated CA-125, while preoperative workup excluded colonic adenocarcinoma but could not rule out GIST or other tumors; endoscopic biopsy was inconclusive for the obstruction. Intraoperatively, a hard solid sigmoid mass with an attached jejunal loop led to sigmoidectomy performed for presumed malignancy, and histology confirmed intramural endometriosis with two involved nodes. This paper is centrally about endometriosis — deeply infiltrating sigmoid endometriosis with lymph node involvement simulating an obstructive neoplasm.

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Abstract

A rare case of endometriosis of the sigmoid with lymph node involvement is described in a 35-yea-rold patient. The patient presented with a 12-month history of abdominal pain and diarrhoea with catamenial aggravation. A full clinical and laboratory investigation was performed with normal results, with the exception of the tumour marker CA-125 which was elevated. An abdominal CT scan demonstrated an eccentric bowel wall thickening of the sigmoid colon. Colonoscopy revealed extensive stenosis of the bowel lumen covered by normal mucosa. The histopathology results of an endoscopic biopsy were inconclusive in regard to the nature of the obstruction. Preoperative assessment excluded colonic adenocarcinoma but could not rule out the possibility of a gastrointestinal stromal tumour (GIST) or other type of tumour. Nevertheless, the diagnosis of endometriosis appeared more likely. Intraoperatively, a solid, hard tumour of the sigmoid colon was palpated with a jejunal loop attached to it; consequently, sigmoidectomy for malignancy was decided as the optimal plan of action. There was no evidence of additional pathology in the abdominal cavity. Histology of the specimen revealed intramural endometriosis of the sigmoid with involvement of two regional nodes. Treatment options for large bowel endometriosis include hormonal manipulation with additional surgical resection depending on the patient’s age, the severity and the potential complications of the disease. Similar content being viewed by others

References

Craig A. Winkel “Evaluation and Management of Women With Endometriosis” Obstetrics & Gynecology. 2003; 102(2): 397–408 Jubanyik KJ, Comite F. “Extrapelvic endometriosis.” Obstet Gynecol Clin North Am. 1997; 24(2):411–440 Philippos Dimoulios, Ioannis E Koutroubakis, Maria Tzardi, Pavlos Antoniou, Ioannis M Matalliotakis and Elias A Kouroumalis “A case of sigmoid endometriosis difficult to differentiate from colon cancer” BMC Gastroenterology 2003;3:18–22 Sievert W, Sellin JH, Stringer CA. “Pelvic endometriosis simulating colonic malignant neoplasm.” Arch Intern Med. 1989; 149(4):935–938. S. Mizrahi, O. Mayzler, D. Goldstein, R. Shaco-Levy “Endometriosis simulating a colonic obstructive neoplasm” European Journal of Surgical Oncology, 2003; 29(9):766–767 Scully R.E., Mark E.J. et al. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 13-2000. “A 26-year-old woman with bouts of abdominal pain, vomiting, and diarrhea.” N Engl J Med 2000; 27;342(17):1272–1278 Yantiss RK, Clement PB, Young RH.. “Endometriosis of the intestinal tract: a study of 44 cases of a disease that may cause d verse challenges in clinical and pathologic evaluation.” Am J Surg Pathol. 2001; 25(4):445–454 Insabato L, Pettinato G. “Endometriosis of the bowel with lymph node involvement. A report of three cases and review of the literature.” Pathol Res Pract. 1996; 192(9):957–961; discussion 962 Abrao MS, Podgaec S, Dias Jr JA, Averbach, M, Garry R, Luis Fernando Ferraz Silva, Carvalho FM. “Deeply infiltrating endometriosis affecting the rectum and lymph nodes” Fertility and Sterility 2006; 86(3):543–547 Yantiss RK, Clement PB, Young RH. Neoplastic and preneoplastic changes in gastrointestinal endometriosis: a study of 17 cases. Am J Surg Pathol. 2000; 24(4):513–524. Collin GR, Russell JC. “Endometriosis of the colon. Its diagnosis and management.” Am Surg. 1990; 56(5):275–279. Langlois NE, Park KG, Keenan RA “Mucosal changes in the large bowel with endometriosis: a possible cause of misdiagnosis of colitis?» Hum Pathol. 1994; 25(10):1030–1034 Brosens J, Timmerman D, Starzinski-Powitz A, Brosens I. “Noninvasive diagnosis of endometriosis: the role of imaging and markers.” Obstet Gynecol Clin North Am. 2003; 30(1):95–114, viii–ix. Goncalves MO, Podgaec S, Dias JA Jr, Gonzalez M, Abrao MS. “Transvaginal ultrasonography with bowel preparation is able to predict the number of lesions and rectosigmoid layers affected in cases of deep endometriosis, defining surgical strategy.” Hum Reprod. 2010 Mar;25(3):665–671. Ayman Al-Talib & Togas Tulandi “Intestinal endometriosis” Gynecol Surg. 2010; 7:61–62 Zardawi I. “Aggressive endometriosis.” Int J Gynecol Cancer 2003; 13:98–100 Scolyer RA, Carter J, Russell P. “Aggressive endometriosis: report of a case.” Int J Gynecol Cancer. 2000; 10(3):257–262 Yan M, Boulas J, Russell P. “Aggressive endometriosis with focal change suggesting early neoplastic transformation.” Pathology. 2007; 39(4):450–453. Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Mylonakis, E., Maroufidis, G., Klimis, A. et al. Deeply infiltrating endometriosis of the sigmoid and lymph nodes simulating obstructive neoplasm. Hellenic J Surg 82, 337–341 (2010). https://doi.org/10.1007/s13126-010-0053-3 Received: Accepted: Published: Issue date: DOI: https://doi.org/10.1007/s13126-010-0053-3

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