Interstitial Cystitis and Pelvic Pain: Understanding and Treating at the Primary Care Level

In: Urogynecology in Primary Care · 2007 · pp. 137–151 · doi:10.1007/978-1-84628-167-9_13 · W77016444
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Primary care providers are essential in recognizing and treating chronic pelvic pain, a common condition affecting millions of women annually with significant societal costs.

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This paper/chapter reviews chronic pelvic pain and focuses on interstitial cystitis, framing how primary care providers can recognize and manage women with chronic pelvic pain. It uses epidemiologic data and prior clinical literature to describe the burden of chronic pelvic pain, its frequency in gynecologic practice settings, and the clinical context in which interstitial cystitis is diagnosed, including mention of diagnostic concepts and criteria used in the literature. A major limitation is that the provided text is primarily a high-level narrative/educational overview rather than original research with study-specific methods, eligibility criteria, or outcomes. Relevance to endometriosis: the chapter cites evidence-based discussions of endometriosis-associated chronic pelvic pain and includes endometriosis studies in its reference list, though its main focus is interstitial cystitis and chronic pelvic pain in primary care.

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Abstract

Chronic pelvic pain is defi ned as pain in the pelvis of greater than six months’ duration. It is estimated that 3.8% of women aged 15—73 have chronic pelvic pain which is more common than asthma or migraines.1 Chronic pelvic pain directly costs society $880 million dollars per year.2 It has been reported that approximately 10% of visits to the gynecologist, 20% to 40% of gynecologic diagnostic laparoscopies, and 12% to 20% of hysterectomies performed are for complaints of chronic pelvic pain.3 Primary care providers will often be presented with these complaints from their female patients and can play a vital role in recognizing and treating this important women’s health condition. Preview Unable to display preview. Download preview PDF. Similar content being viewed by others

References

Zondervan KT, Yudkin PL, Vessey MP, Dawes MG, Barlow DH, Kennedy SH. Prevalence and incidence of chronic pelvic pain in primary care: evidence from a national general practice database. Br J Obstet Gynaecol. 1999;106:1149–1155. Mathias SD, Kuppermann M, Liberman RF, Lipschutz RC, Steege JF. Chronic pelvic pain: prevalence, health-related quality of life, and economic correlates. Obstet Gynecol. 1996;87:321–327. Reiter RC, Gambone JC. Demographic and historic variables in women with idiopathic chronic pelvic pain. Obstet Gynecol. 1990;75:428–432. Rogers RM. Basic pelvic neuroanatomy. In Steege JF, Metzger DA, Levy BS, eds. Chronic Pelvic Pain: An Integrated Approach. Philadelphia: W.B. Saunders Co., 1998:31–58. Moore K. The Developing Human: Clinically Oriented Embryology. 4th ed. Philadelphia, W.B. Saunders Co., 1988. Bussolati G, Tizzani A, Casetta G et al. Detection of estrogen receptors in the trigonum and urinary bladder with an immunohistochemical technique. Gynecol Endocrinol. 1990;4:205–213. Tao YX, Heit M, Lei ZM, Rao CV. The urinary bladder of a woman is a novel site of luteinizing hormone-human chorionic gonadotropin receptor gene expression. Am J Obstet Gynecol. 1998;179: 1026–1031. Xiao ZL, Pricolo V, Biancani P, Behar J. Role of progesterone signaling in the regulation of Gprotein levels in female chronic constipation. Gastroenterology. 2005 Mar;128(3):667–675. Shiah IS, Yatham LN. GABA function in mood disorders: an update and critical review. Life Sci. 1998;63(15):1289–1303. Cyriax EF. On various conditions that may stimulate the referred pains of visceral disease, and a consideration of these from the point of view of cause and effect. Practitioner. 1919;102:314–322. Carnett JB. Intercostal neuralgia as a cause of abdominal pain and tenderness. Surg Gynecol Obstet. 1926;42:625–632. Carter JE. Surgical treatment for chronic pelvic pain. JSLS. 1998;2:129–139. Howard FM. Chronic pelvic pain. Obstet Gynecol. 2003 Mar;101:594–611. Ringel Y, Sperber AD, Drossman DA. Irritable Bowel Syndrome. Annu Rev Med. 2001;52:319–338. Case AM, Reid RL. Menstrual cycle effects on common medical conditions. Compr Ther. 2001;27: 65–71. Vanner SJ, Depew WT, Paterson WG et al. Predictive value of the Rome criteria for diagnosing the irritable bowel syndrome. Am J Gastroenterol. 1999 Oct;94:2912–2917. Eliakim R, Abulafia O, Sherer DM. Estrogen, progesterone and the gastrointestinal tract. J Reprod Med. 2000;45:781–788. Speroff L, Glass RH, Kase NG. Clinical Gynecologic Endocrinology and Infertility. 5th ed. Baltimore, MD: William and Wilkins, 1994. Koninckx PR, Meuleman C, Demeyere S, Lesaffre E, Cornillie FJ. Suggestive evidence that pelvic endometriosis is a progressive disease whereas deeply infiltrating endometriosis is associated with pelvic pain. Fertil Steril. 1991;55:759–765. Marcoux S, Maheux R, Berube S. Laparascopic Surgery in Infertile Women with Minimal or Mild Endometriosis. Canadian Collaborative Group on Endometriosis. N Engl J Med. 1997;337:217–222. Howard FM. An evidence-based medicine approach to the treatment of endometriosis-associated chronic pelvic pain: placebo-controlled studies. J Am Assoc Gynecol Laparosc. 2000 Nov;7:477–488. Hemsell DL. ACOG educational bulletin: Antibiotics and gynecologic infections. In: American College of Obstetrics/Gynecology 2001 Compendium. Washington, DC: ACOG; 2001;237:302–309. Howard FM, El-Minawi AM, Sanchez RA. Conscious pain mapping by laparoscopy in women with chronic pelvic pain. Obstet Gynecol. 2000;96: 934–939. Baggish MS, Miklos JR. Vulvar Pain Syndrome: A Review. Obstet Gynecol Surv. 1995;50:618–627. Metts JF. Vulvodynia and vulvar vestibulitis: challenges in diagnosis and management. Am Fam Physician. 1999;59:1547–1556. Byth JL. Understanding vulvodynia. Australas J Dermatol. 1998;39:139–148. Bergeron S, Binik TM, Khalife S, Pagidas K. Vulvar vestibulitis syndrome: a critical review. Clin J Pain. 1997;13(1):27–42. Harger JH. Genital herpes simplex infections. Contem OB/Gyn. 1997;April:21–41. Walling MK, Reiter RC, O’Hara MW, Milburn AK, Lilly G, Vincent SD. Abuse history and chronic pain in women: I. Prevalences of sexual abuse and physical abuse. Obstet Gynecol. 1994 Aug;84(2):193–199. Clemons JL, Arya LA, Myers DL. Diagnosing interstitial cystitis in women with chronic pelvic pain. Obstet Gynecol. 2002 Aug;100:337–341. Parsons CL, Dell J, Stanford EJ et al. Increased prevalence of interstitial cystitis: previously unrecognized urologic and gynecologic cases identified using a new symptom questionnaire and intravesical potassium sensitivity. Urology. 2002 Oct;60(4): 573–578. Oravisto KJ. Epidemiology of interstitial cystitis. Ann Chir Gynaecol Fenn. 1975;64:75–77. Parsons CL. Interstitial cystitis: clinical manifestations and diagnostic criteria in over 200 cases. Neurourol Urodyn. 1990;9:241–250. Simon LJ, Landis JR, Erickson DR, Nyberg LM. The Interstitial Cystitis Database Study: concepts and preliminary baseline descriptive statistics. Urol. 1997;49(5A):64–75. O’Leary MP, Sant GR, Fowler FJ Jr., Whitmore KE, Spolarich-Kroll J. The interstitial cystitis symptom and problem index. Urol. 1997 May;49(5A Suppl): 58–63. Parsons CL, Stein PC, Bidair M, Lebow D. Abnormal sensitivity to intravesical potassium in interstitial cystitis and radiation cystitis. Neurourol Urodyn. 1994;9:515–520. Parsons CL, Greenberger M, Gabal L, Bidair M, Barme G. The role of urinary potassium in the pathogenesis and diagnosis of interstitial cystitis. J Urol. 1998;159:1862–1866. Ripoll E, Mahowald D. Hatha Yoga therapy management of urologic disorders. World J Urol. 2002 Nov;20:306–309. Parson CL, Mulholland SG. Successful therapy of interstitial cystitis with pentosanpolysulfate. J Urol. 1987;138:513–516. van Ophoven A, Oberpenning F, Hertle L. Longterm results of trigone-preserving orthotopic substitution enterocystoplasty for interstitial cystitis. J Urol. 2002 Feb;167:603–607. Nielsen KK, Kromann-Andersen B, Steven K, Hald T. Failure of combined supratrigonal cystectomy and Mainz ileocecocystoplasty in intractable interstitial cystitis: is histology and mast cell count a reliable predictor for the outcome of surgery? J Urol. 1990;144:255–259. Editor information Editors and Affiliations Rights and permissions Copyright information © 2007 Springer-Verlag London Limited About this chapter Cite this chapter Myers, D.L. (2007). Interstitial Cystitis and Pelvic Pain: Understanding and Treating at the Primary Care Level. In: Culligan, P.J., Goldberg, R.P. (eds) Urogynecology in Primary Care. Springer, London. https://doi.org/10.1007/978-1-84628-167-9_13 Download citation DOI: https://doi.org/10.1007/978-1-84628-167-9_13 Publisher Name: Springer, London Print ISBN: 978-1-84628-166-2 Online ISBN: 978-1-84628-167-9 eBook Packages: MedicineMedicine (R0)

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