Menstrual cycle effects on common medical conditions

Menstrual cycle-related exacerbation of common medical conditions such as migraine, epilepsy, asthma, irritable bowel syndrome, and diabetes, is a well-recognized phenomenon. Accurate documentation of symptoms on a menstrual calendar allows identification of women with cyclic alterations in disease activity. Similar content being viewed by others

Dalton K. The influence of menstruation an health and disease. Proc R Soc Med. 1964;57:18. Magos A, Studd J. Effects of the menstrual cycle on medical disorders. Br J Hosp Med. 1985;33:68–77. Tuch RH. The relationship between a mother's menstrual status and her response to illness in her child. Psychosom Med. 1975;37:388–394. Reid RL, Van Vugt DA. Neuroendocrine events that regulate the menstrual cycle. Contemp Obstet Gynecol. 1987;30:147–155. Speroff L, Glass RH, Kase NG: Clinical Gynecologic Endocrinology and Infertility, 5th ed. Baltimore: Williams and Wilkins. 1994. Reid RL. Use of GnRH agonists for menstrual cycle-related disorders. J SOGC. 1992;14(8):59–65. Mortola JF, Girton L, Fischer U. Successful treatment of severe premenstrual syndrome by combined use of gonadotropin-releasing hormone agonist and estrogen/progestin. J Clin Endocrinol Metab. 1991;72:252A-252F. Linet MS, Stewart WF. Migraine headache: epidemiologic perspectives. Epidemiol Rev. 1984;6:107–139. Digre K, Damasio H. Menstrual migraine: differential diagnosis, evaluation, and treatment. Clin Obstet Gynecol. 1987; 30:417–430. Marcus DA. Focus on primary diagnosis and management of headache in women. Obstet Gynecol Surv. 1999;54:395–402. MacGregor EA, Chia H, Vohrah RC, Wilkinson M. Migraine and menstruation: a pilot study. Cephalalgia. 1990;10:305–310. Dalessio DJ. In: Wolff's Headache and Other Head Pain. New York: Oxford University Press. 1980. Salvatore CA. Arteriole supply in normal and hyperplastic endometrium. Am J Obstet Gynecol. 1968;102:493–500. Grant ECG. Relation of arterioles in the endometrium to headache from oral contraceptives. Lancet. 1965;1:1143–1144. Grant ECG. Relation between headache from oral contraceptives and development of endometrial arterioles. Br Med J. 1968;2:402–405. Somerville BW. The role of estradiol withdrawal in the etiology of menstrual migraine. Neurology. 1972;22:355–365. Whitty CWM, Hockaday JM, Whitty MM. The effect of oral contraceptive on migraine. Lancet. 1966;1:856–859. Stein GS. Headaches in the first post partum week and their relationship to migraine. Headache. 1981;21:201–205. Neri I, Granella F, Nappi R, Manzoni GC, Facchinetti F, Genazaani AR. Characteristics of headache at menopause: a clinico-epidemiologic study. Maturitas. 1993;17:31–37. Silberstein SD, Merriam GR. Estrogens, progestins, and headache. Neurology. 1991;41:786–793. DeLignières B, Vincens M, Mauvais-Jarvis P, Mas JL, Touboul PJ, Bousser MG. Prevention of menstrual migraine by percutaneous oestradiol. Br Med J. 1986;293:1540. Magos AL, Zikha KJ, Studd JWW. Treatment of menstrual migraine by oestradiol implants. J Neurol Neurosurg Psychiatry. 1983;46:1044–1046. Somerville BW. Estrogen-withdrawal migraine: I. Duration of exposure required and attempted prophylaxis by premenstrual estrogen administration. Neurology. 1975;25:239–244. Somerville BW. Estrogen-withdrawal migraine. II. Attempted prophylaxis by continuous estradiol administration. Neurology. 1975;25:245–250. Pfaffenrath V. Efficacy and safety of percutaneous estradiol vs placebo in menstrual migraine. Cephalalgia. 1993;13 [Suppl 13]:244. MacGregor EA. Menstruation, sex hormones, and migraine. Neurol Clin. 1997;15:125–141. Sarrell PM. Blood flow and ovarian secretions. In: Naftolin F, DeCherney A, Gutmann JN, Sarrel PM, eds. Ovarian Secretions and Cardiovascular and Neurological Function. Vol 80. New York, NY: Raven Press; 1990:81–89. Murray SC, Muse KN. Effective treatment of severe menstrual migraine headaches with gonadotropin-releasing hormone agonist and “add-back” therapy. Fertil Steril. 1997;67:390–393. Boggess KA, Williamson HO, Homm RJ. Influence of the menstrual cycle on systemic disease. Obstet Gynecol Clin North Am. 1990;17:321–342. Duncan S, Read CL, Brodie MJ. How common is catamenial epilepsy?. Epilepsia. 1993;34:827–831. Newmark ME, Penry JK. Catamenial epilepsy: a review. Epilepsia. 1980;21:281–300. Bäckström T. Epileptic seizures in women related to plasma estrogen and progesterone during the menstrual cycle. Acta Neurol Scand. 1976;54:321–347. Zimmerman AW. Hormones and epilepsy. Neurol Clin. 1986;4:853–861. Bäckström T, Zetterlund B, Blom S, Romano M. Effects of intravenous progesterone infusions on the epileptic discharge frequency in women with partial epilepsy. Acta Neurol Scand. 1984;69:240–248. Mattson RH, Kamer JA, Cramer JA, Caldwell BV. Seizure frequency and the menstrual cycle: a clinical study. Epilepsia. 1981;22:242. Kumar N, Behari M, Aruja GK, Jailkhani BL. Phenytoin levels in catamenial epilepsy. Epilepsia. 1988;29:155–158. Liporace JD. Women's issues in epilepsy. Menses, childbearing and more. Postgrad Med. 1997;102:123–124, 127–129, 133–135. Dana-Haeri J, Richens A. Effect of norethisterone on seizures associated with menstruation. Epilepsia. 1983;24:377–381. Hall SM. Treatment of menstrual epilepsy with a progesterone-only oral contraceptive. Epilepsia. 1977;18:235–236. Herzog AG. Intermittent progesterone therapy and frequency of complex partial seizures in women with menstrual disorders. Neurology. 1986;36:1607–1610. Holmes GL. Effects of menstruation and pregnancy on epilepsy. Semin Neurol. 1988;8:234–239. Settipane RA, Simon RA. Menstrual cycle and asthma. Ann Allergy. 1989;63:373–378. Hanley SP. Asthma variation with menstruation. Br J Dis Chest. 1981;75:306–308. Gibbs CJ, Counts II, Lock R, Finnegan OC, White RJ. Premenstrual exacerbations of asthma. Thorax. 1984;39:833–836. Ozkaragoz K, Cakin F. The effect of menstruation on immediate skin reactions in patients with respiratory allergy. J Asthma Res. 1970;7:171–175. Beynon HLC, Garbett ND, Barnes PJ. Severe premenstrual exacerbations of asthma: effect of intramuscular progesterone. Lancet. 1988;2:370–372. Blumenfeld Z, Bentur L, Yoffe N, Alroy G, Rubin AE. Menstrual asthma: use of a gonadotropin-releasing hormone analogue for the treatment of cyclic aggravation of bronchial asthma. Fertil Steril. 1994;62:197–200. Sandler RS. Epidemiology of irritable bowel syndrome in the United States. Gastroenterology. 1990;99:409–412. Schuster M. Diagnostic evaluation of the irritable bowel syndrome. Gastroenterol Clin North Am. 1991;20:269–278. Whitehead WE, Cheskin LJ, Heller BR, et al. Evidence for exacerbation of irritable bowel syndrome during menses. Gastroenterology. 1990;98:1485–1489. Mathias JR, Clench MH, Reeves-Darby VG, et al. Effect of leuprolide acetate in patients with moderate to severe functional bowel disease. Double-blind, placebo controlled study. Dig Dis Sci. 1994;39:1155–1162. Fisher RS, Roberts GS, Grabowski CJ, Cohen S. Inhibition of lower esophageal sphincter circular muscle by female sex hormones. Am J Physiol. 1978;234:E243-E247. Wald A, Van Thiel DH, Hoechstetter L, et al. Gastrointestinal transit: the effect of the menstrual cycle. Gastroenterology. 1981;80:1497–1500. Turnbull GK, Thompson DG, Day S, Martin J, Walker E, Lennard-Jones JE. Relationships between symptoms, menstrual cycle and orocaecal transit in normal and constipated women. Gut. 1989;30:30–34. Heitkemper M, Jarrett M. Pattern of gastrointestinal and somatic symptoms across the menstrual cycle. Gastroenterology. 1992;102:505–513. Moore J, Barlow D, Jewell D, Kennedy S. Do gastrointestinal symptoms vary with the menstrual cycle? Br J Obstet Gynaecol. 1998;105:1322–1325. Widom B, Diamond MP, Simonson DC. Alterations in glucose metabolism during menstrual cycle in women with IDDM. Diabetes Care. 1992;15:213–220. Letterie GS, Fredlund PN. Catamenial insulin reactions treated with a long-acting gonadotropin releasing hormone agonist. Arch Intern Med. 1994;154:1868–1870. Walsh CH, Malins JM. Menstruation and control of diabetes. Br Med J. 1977;2:177–179. Hubble D. Insulin resistance. Br Med J. 1954;2:1022. Bertoli A, De Pirro R, Fusco A, Greco AV, Magnatta R, Lauro R. Differences in insulin receptors between men and menstruating women and influence of sex hormones on insulin binding during the menstrual cycle. J Clin Endocrinol Metab. 1980;50:246–250. Jarrett RJ, Graver HJ. Changes in oral glucose tolerance during the menstrual cycle. Br Med J. 1968;2:528–529. Tomelleri R, Gruewald K. Menstrual cycle and food cravings in young college women. J Am Diet Assoc. 1987;87:311–315. Maurer ER, Schaal FA, Mendez FL. Chronic recurring spontaneous pneumothorax due to endometriosis of the diaphragm. JAMA. 1958;168:2013–2024. Markham SM, Carpenter SE, Rock JA. Extrapelvic endometriosis. Obstet Gynecol Clin North Am. 1989;16:193–207. Slabbynck H, Laureys M, Impens N, De Vroey P, Schandevyl W. Recurring catamenial pneumothorax treated with a GnRH analogue. Chest. 1991;100:851. Arnbjornsson E. Acute appendicitis risk in various phases of the menstrual cycle. Acta Chir Scand. 1983;149:603–605. Arnbjornsson E. The influence of oral contraceptives on the frequency of acute appendicitis in different phases of the menstrual cycle. Surg Gynecol Obstet. 1984;158:464–466. Dalton K. Influence of menstruation on glaucoma. Br J Ophthalmol. 1967;51:692–695. Smith R, Studd JW. A pilot study of the effect upon multiple sclerosis of the menopause, hormone replacement therapy and the menstrual cycle. J R Soc Med. 1992;85:612–613. Caughey SC, Margesson LJ, Reid RL. Erythema multiforme with ulcerative stomatitis at menstruation. Can J Obstet Gynecol. 1990;112–113. Howard RE. Premenstrual urticaria and dermatographism. JAMA. 1981;245:1068. Rosano GMC, Leonardo F, Sarrel P, Beale CM, De Luca F, Collins P. Cyclical variation in paroxysmal supraventricular tachycardia in women. Lancet 1996;347:786–88. Anderson KE, Spitz IM, Sassa S, Bardin W, Kappas A. Prevention of cyclical attacks of acute intermittent porphyria with a long-acting agonist of luteinizing hormone-releasing hormone. N Eng J Med. 1984;311:643–645. Meggs WJ, Pescovitz OH, Metcalfe D, Loriaux DL, Cutler G Jr., Kaliner M. Progesterone sensitivity as a cause of recurrent anaphylaxis. N Eng J Med. 1984;311:1236–1238. Slater JE, Raphael G, Cutler GB Jr., Loriaux DL, Meggs WJ, Kaliner N. Recurrent anaphylaxis in menstruating women: treatment with a luteinizing hormone-releasing hormone agonist—a preliminary report. Obstet Gynecol. 1987;70:542–546. Vijayan N, Vijayan VK, Dreyfuss PM. Acetylcholinesterase activity and menstrual remissions in myasthenia gravis. J Neurol Neurosurg Psychiatry. 1977;40:1060–1065. Badwe RA, Gregory WM, Chaudary MA, et al. Timing of surgery during menstrual cycle and survival of premenopausal women with operable breast cancer. Lancet. 1991;337:1261–1264. Wobbes T, Thomas CM, Segers MF, Peer PG, Bruggink ED, Beex LV. The phase of the menstrual cycle has no influence on the disease-free survival of patients with mammary carcinoma. Br J Cancer. 1994;69:599–600. Author information Authors and Affiliations About this article Cite this article Case, A.M., Reid, R.L. Menstrual cycle effects on common medical conditions. Compr Ther 27, 65–71 (2001). https://doi.org/10.1007/s12019-001-0010-8 Received: Accepted: Issue date: DOI: https://doi.org/10.1007/s12019-001-0010-8