Endometriosis: a reappraisal of pathogenesis and treatment

C L Schmidt, Schmidt CL
Fertility and sterility · 1985 · doi:10.1016/s0015-0282(16)48729-7 · PMID:3894056
review OA: closed public-domain-us ⤵ 1 in-corpus citation
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This paper reappraises the pathogenesis and treatment of endometriosis, highlighting current challenges in understanding its immunologic and hormonal aspects and the limitations of existing therapies.

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Abstract

The enigmatic disease of endometriosis continues to baffle both the scientist and the clinician. An encompassing theory of pathogenesis has failed to emerge from contemporary understanding of the immunologic manifestations, the hormonal aberrations, or the evasive infertility associated with endometriosis. Similarly unsettling is the failure of medical or conservative surgical maneuvers to eradicate endometriosis in a manner commensurate with castration. It is hoped that further insight into these areas of research will resolve both of these dilemmas.

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Condition tags

endometriosisinfertility

MeSH descriptors

Endometriosis Autoimmune Diseases Danazol Danazol Endometriosis Endometriosis Endometriosis Endometriosis Female Humans Infertility, Female Infertility, Female Luteal Phase Menstruation Disturbances Menstruation Disturbances Methyltestosterone Methyltestosterone Pregnancy Progestins Progestins

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europepmc
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pubmed
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Courtesy of the U.S. National Library of Medicine