Endometriosis-Associated Intestinal Tumours: A Consequence of Long-Term Unopposed Oestrogen?

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AI-generated summary by gemini-2.5-flash-lite, 2026-07-18

A patient who underwent hysterectomy and oophorectomy developed intestinal tumors 13 years later while on long-term estrogen implants, suggesting a potential risk of unopposed estrogen therapy.

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Abstract

A case of malignant transformation in an extra-ovarian site, 13 years after total abdominal hysterectomy and bilateral salpingo-oophorectomy, is discussed in a patient on long-term oestrogen implants, which highlights the potential risks surrounding the use of long-term oestrogen replacement therapy.

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Condition tags

endometriosis

MeSH descriptors

Carcinoma, Endometrioid Endometriosis Hormone Replacement Therapy Ovarian Neoplasms Rectal Neoplasms Carcinoma, Endometrioid Carcinoma, Endometrioid Cell Transformation, Neoplastic Endometriosis Endometriosis Female Hormone Replacement Therapy Humans Hysterectomy Incidental Findings Middle Aged Ovarian Neoplasms Rectal Neoplasms Rectal Neoplasms Recurrence

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Cited by (9)

Source provenance

europepmc
last seen: 2026-08-21T06:14:13.963979+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:14:18.065553+00:00
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