Possible de novo clear cell carcinoma in the contralateral ovary 9 years after fertility-sparing surgery for Stage IA clear cell ovarian carcinoma

Keiko Nishida, K Nishida, Yuri Tenjimbayashi, Y Tenjimbayashi, N Tasaka, Nobutaka Tasaka, Ayumi Shikama, A Shikama, M Sakuraiv, Sari Nakao, S Nakao, H Ochi, Hiroyuki Ochi, Takeo Minaguchi, T Minaguchi, Toyomi Satoh, T Satoh
International cancer conference journal · 2016 · vol. 6(2) , pp. 50–54 · doi:10.1007/s13691-016-0271-9 · PMID:31149470 · PMC6498281 · W2550694760
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Abstract

A patient who underwent fertility-sparing surgery for Stage IA clear cell carcinoma may have developed de novo clear cell carcinoma in the contralateral ovary 9 years later. She underwent fertility-sparing surgery and postoperative adjuvant chemotherapy for right ovarian carcinoma at 33 years of age (when endometriosis was observed in the contralateral ovary). At the age of 41 years, a tumor was discovered in the left ovary. This was diagnosed pathologically as clear cell carcinoma with clear cell adenofibroma, which may have developed de novo. A consensus is currently taking shape that although fertility-sparing surgery is a therapeutic option for patients with Stage IA clear cell carcinoma, long-term outpatient monitoring is advised to watch for its recurrence or de novo development in the contralateral ovary.

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endometriosis

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