Toyomi Satoh

Familial Mediterranean fever (FMF) is a juvenile-onset autoinflammatory disease involving recurrent peritonitis. Although the pathogenesis of the disease remains unclear, FMF is caused by dysfunction of the pyrin protein, which suppresses t…

PURPOSE: This study aimed to compare MRI findings among benign, borderline, and malignant ovarian seromucinous neoplasms. METHODS: We retrospectively analyzed MRI data from 24 patients with ovarian seromucinous neoplasms-seven benign, thir…

OBJECTIVES: To investigate the frequency and patterns of calcification in ovarian tumours and evaluate their association with various histological types and malignancy grades. METHODS: This retrospective study included patients who underwe…

OBJECTIVE: This multi-center retrospective study aimed to clarify the characteristics, diagnostic accuracy, treatment outcomes, and prognostic factors of uterine serous carcinoma (USC) in Japanese women. METHODS: The medical records of 193…

Low-grade endometrial stromal sarcoma (LGESS) is a rare mesenchymal tumor of female genital tract malignancies. While it primarily arises in the uterus, extrauterine cases, including those originating in the ovary, are exceedingly rare. Whi…

PURPOSE: To assess the utility of apparent diffusion coefficient maps (ADC) for diagnosing myometrial invasion (MI) in endometrial cancer (EC). METHODS: This retrospective study included 164 patients (mean age, 56 years; range, 25-89 years…

BACKGROUND: Preoperative assessment of the histological type of ovarian cancer is essential to determine the appropriate treatment strategy. Tumor location may be helpful in this regard. The purpose of this study was to compare the position…

BACKGROUND: This study aimed to compare deep learning with radiologists' assessments for diagnosing ovarian carcinoma using MRI. METHODS: This retrospective study included 194 patients with pathologically confirmed ovarian carcinomas or bo…

BACKGROUND: Ovarian clear cell carcinoma (OCCC) is one of the most lethal types of ovarian cancer. Early-stage OCCC can be cured by surgery; however, advanced-stage disease shows poor prognosis due to chemoresistance unlike the more common …

PURPOSE: To verify whether deep learning can be used to differentiate between carcinosarcomas (CSs) and endometrial carcinomas (ECs) using several magnetic resonance imaging (MRI) sequences. MATERIAL AND METHODS: This retrospective study i…

Elevated serum levels of cancer antigen 125 (CA125) are known to occur in adenomyosis. However, the relationship between the severity of adenomyosis and serum CA125 levels has not yet been elucidated. The present study aimed to examine the …

PURPOSE: To clarify imaging and clinical characteristics of ovarian carcinosarcoma (CS) compared with high-grade serous carcinoma (HGSC). METHODS: We retrospectively reviewed MR imagings of 12 patients with CS and 30 patients with HGSC and…

We report the case of a 30-year-old woman who complained of a painful palpable mass. Magnetic resonance imaging revealed an ill-defined mass approximately 8 cm in diameter with internal microcytic components. The mass diffusely involved the…

Dienogest is a novel synthesized progestin used for treatment of endometriosis. This is the first case report describing a therapeutic effect of dienogest on a gynecologic malignancy. The patient was a 44-year-old woman with advanced adenos…

BACKGROUND: Primary epithelial ovarian carcinoma is sub-classified into serous, mucinous, endometrioid and clear cell subtypes. Neoadjuvant chemotherapy has become an alternative treatment option past several years, as serous carcinoma, the…

A patient who underwent fertility-sparing surgery for Stage IA clear cell carcinoma may have developed de novo clear cell carcinoma in the contralateral ovary 9 years later. She underwent fertility-sparing surgery and postoperative adjuvant…

OBJECTIVE: To determine the long-term outcomes of patients with an isolated ovarian recurrence after fertility sparing surgery (FSS) for epithelial ovarian cancer (EOC) and to evaluate the recurrence rates (and location) according to the ne…

Dienogest is a novel synthesized progestin used for treatment of endometriosis. This is the first case report describing a therapeutic effect of dienogest on a gynecologic malignancy. The patient was a 44-year-old woman with advanced adenos…

OBJECTIVE: Although mural nodules are considered to be the most important hallmark in the recognition of ovarian cancers accompanied with endometriotic cysts, benign neoplasms and even inflammatory diseases can show similar MRI findings. We…