Niche role of MRI in the evaluation of female infertility

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This review highlights MRI's niche role in diagnosing complex adnexal masses, endometriosis, and Mullerian duct anomalies when pelvic ultrasound is inconclusive for female infertility evaluation.

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This review discusses imaging selection for female infertility, outlining pelvic causes by ovarian, tubal/peritubal, and uterine disorders and describing how hysterosalpingography (HSG) is used first for tubal patency, with further characterization by ultrasound, sono-hysterography, or pelvic MRI when ultrasound is inconclusive. It reports that hysterographic ultrasound has limitations in visualizing extraluminal pathology, and that transabdominal/transvaginal ultrasound may remain unresolved for entities such as extensive pelvic inflammatory disease, complex tubo-ovarian pathology, deep-seated endometriosis with complications, Müllerian duct anomalies, uterine synechiae, and adenomyosis, for which MRI has a “niche” role in resolving complex adnexal masses and related anomalies. A stated caveat is that the review is based on the authors’ experience at tertiary care teaching hospitals rather than a systematic evidence synthesis. Relevance to endometriosis: the paper explicitly highlights MRI as resolving “deep-seated endometriosis deposits with its related complications” and includes endometriosis among the infertility causes where ultrasound may be inconclusive, though its main focus is an imaging approach for complex female infertility evaluation.

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Abstract

Infertility is a major social and clinical problem affecting 13-15% of couples worldwide. The pelvic causes of female infertility are categorized as ovarian disorders, tubal, peritubal disorders, and uterine disorders. Appropriate selection of an imaging modality is essential to accurately diagnose the aetiology of infertlity, since the imaging diagnosis directs the appropriate treatment to be instituted. Imaging evaluation begins with hystero- salpingography (HSG), to evaluate fallopian tube patency. Uterine filling defects and contour abnormalities may be discovered at HSG but usually require further characterization with pelvic ultrasound (US), sono-hysterography (syn: hystero-sonography/saline infusion sonography) or pelvic magnetic resonance imaging (MRI), when US remains inconclusive. The major limitation of hysterographic US, is its inability to visualize extraluminal pathologies, which are better evaluated by pelvic US and MRI. Although pelvic US is a valuable modality in diagnosing entities comprising the garden variety, however, extensive pelvic inflammatory disease, complex tubo-ovarian pathologies, deep-seated endometriosis deposits with its related complications, Mulllerian duct anomalies, uterine synechiae and adenomyosis, often remain unresolved by both transabdominal and transvaginal US. Thus, MRI comes to the rescue and has a niche role in resolving complex adnexal masses, endometriosis, and Mullerian duct anomalies with greater ease. This is a review, based on the authors' experience at tertiary care teaching hospitals and aims to provide an imaging approach towards the abnormalities which are not definitively diagnosed by ultrasound alone.
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Abstract

Infertility is a major social and clinical problem affecting 13–15% of couples worldwide. The pelvic causes of female infertility are categorized as ovarian disorders, tubal, peritubal disorders, and uterine disorders. Appropriate selection of an imaging modality is essential to accurately diagnose the aetiology of infertlity, since the imaging diagnosis directs the appropriate treatment to be instituted. Imaging evaluation begins with hystero- salpingography (HSG), to evaluate fallopian tube patency. Uterine filling defects and contour abnormalities may be discovered at HSG but usually require further characterization with pelvic ultrasound (US), sono-hysterography (syn: hystero-sonography/saline infusion sonography) or pelvic magnetic resonance imaging (MRI), when US remains inconclusive. The major limitation of hysterographic US, is its inability to visualize extraluminal pathologies, which are better evaluated by pelvic US and MRI. Although pelvic US is a valuable modality in diagnosing entities comprising the garden variety, however, extensive pelvic inflammatory disease, complex tubo-ovarian pathologies, deep-seated endometriosis deposits with its related complications, Mulllerian duct anomalies, uterine synechiae and adenomyosis, often remain unresolved by both transabdominal and transvaginal US. Thus, MRI comes to the rescue and has a niche role in resolving complex adnexal masses, endometriosis, and Mullerian duct anomalies with greater ease. This is a review, based on the authors’ experience at tertiary care teaching hospitals and aims to provide an imaging approach towards the abnormalities which are not definitively diagnosed by ultrasound alone.

Keywords

Complex tubo-ovarian pathologies - endometriosis - female infertility - HSG - MR imaging - MRI - Mullerian duct anomaliesPublication History Received: 13 September 2019 Accepted: 11 February 2020 Article published online: 19 July 2021 © 2020. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/). Thieme Medical and Scientific Publishers Private Ltd. A-12, Second Floor, Sector -2, NOIDA -201301, India -

References

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