The effects of implanon in the symptomatic treatment of endometriosis.
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This study found that the progestin implant Implanon effectively reduced pain and menstrual symptoms in 50 women with symptomatic endometriosis over 12 weeks.
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Abstract
OBJECTIVE: To evaluate the efficacy of Implanon on treatment of symptomatic endometriosis DESIGN: An open clinical study without control group SETTING: Family Planning Clinic and out patient department, King Chulalongkorn Memorial Hospital, Bangkok, Thailand. MATERIAL AND METHOD: A total number of 50 women with symptomatic endometriosis who were diagnosed and confirmed by laparoscopy or whose symptoms recurred after surgical treatment were recruited in the study. These subjects were implanted Implanon subcutaneously at medial aspect of non-dominant forearm. The intensity of pain was assessed with Visual Analog Scale (VAS) before insertion and at 4th and 12th weeks after the insertion. The adverse effects were recorded by the patients in 4th and 12th weeks of treatment. The women evaluated their satisfaction on treatment at the end of study. RESULTS: 50 women recruited in the study and all completed follow-up. Improvements of pain severity and menstrual symptoms were observed. The mean + SD Visual Analog Scale score of dysmenorrheal were 7.08 +/- 2.09 at baseline, 3.72 +/- 2.04 at 4th week, and 0.84 +/- 1.67 at 12th week of treatment. During the study period. regular menstruation, amenorrhea, spotting, and breakthrough bleeding were reported by 21 (42%). 14(28%), 13(26%), and 2(4%). At final satisfaction evaluation, 6(12%) women were very satisfied, 34 (68%) were satisfied, and 10(20%) were uncertain. All of acceptors continued to retaining the implant after study. CONCLUSION: Implanon, a sub-dermalprogestin implant is an effective hormonal alternative for treatment of symptomatic endometriosis. However women should be carefully counseled regarding menstrual changes. has the potential for providing long-term treatment of endometriosis. Nevertheless, the further study should be conducted to compare with other of modality of treatment.
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References (6)
- Conservative laparoscopic excision of endometriosis by sharp dissection: life table analysis of reoperation and persistent or recurrent disease via openalex
- Placebo-controlled comparison of hormonal and biochemical effects of danazol and high-dose medroxyprogesterone acetate via openalex
- The evidence for the management of endometriosis via openalex
- W1512318310 via openalex
- W1983554558 via openalex
- W2465188292 via openalex
Cited by (10)
- Non-contraceptive Effects of Subdermal Levonogestrel Implant on Endometriosis Patient : A Case Report 2021
- The Etonogestrel Contraceptive Implant as a Therapy for Endometriosis 2020
- [Progress on medical treatment in the management of adenomyosis]. 2019
- Hormonal contraception in women with endometriosis: a systematic review 2019
- Tratamientos farmacológicos de la endometriosis (a excepción de la adenomiosis) 2018
- Pharmacologic treatment of the ovarian endometrioma 2016
- Contraception and endometriosis: challenges, efficacy, and therapeutic importance 2015
- Endometriosis 2013
- Brief update on endometriosis treatment 2011
- Endometriosis 2009
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- europepmc
- last seen: 2026-09-04T06:17:57.233406+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:14:48.452140+00:00
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