The effects of implanon in the symptomatic treatment of endometriosis.

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This study found that the progestin implant Implanon effectively reduced pain and menstrual symptoms in 50 women with symptomatic endometriosis over 12 weeks.

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Abstract

OBJECTIVE: To evaluate the efficacy of Implanon on treatment of symptomatic endometriosis DESIGN: An open clinical study without control group SETTING: Family Planning Clinic and out patient department, King Chulalongkorn Memorial Hospital, Bangkok, Thailand. MATERIAL AND METHOD: A total number of 50 women with symptomatic endometriosis who were diagnosed and confirmed by laparoscopy or whose symptoms recurred after surgical treatment were recruited in the study. These subjects were implanted Implanon subcutaneously at medial aspect of non-dominant forearm. The intensity of pain was assessed with Visual Analog Scale (VAS) before insertion and at 4th and 12th weeks after the insertion. The adverse effects were recorded by the patients in 4th and 12th weeks of treatment. The women evaluated their satisfaction on treatment at the end of study. RESULTS: 50 women recruited in the study and all completed follow-up. Improvements of pain severity and menstrual symptoms were observed. The mean + SD Visual Analog Scale score of dysmenorrheal were 7.08 +/- 2.09 at baseline, 3.72 +/- 2.04 at 4th week, and 0.84 +/- 1.67 at 12th week of treatment. During the study period. regular menstruation, amenorrhea, spotting, and breakthrough bleeding were reported by 21 (42%). 14(28%), 13(26%), and 2(4%). At final satisfaction evaluation, 6(12%) women were very satisfied, 34 (68%) were satisfied, and 10(20%) were uncertain. All of acceptors continued to retaining the implant after study. CONCLUSION: Implanon, a sub-dermalprogestin implant is an effective hormonal alternative for treatment of symptomatic endometriosis. However women should be carefully counseled regarding menstrual changes. has the potential for providing long-term treatment of endometriosis. Nevertheless, the further study should be conducted to compare with other of modality of treatment.

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Outcome instruments

VAS-pain

Condition tags

endometriosis

MeSH descriptors

Contraceptive Agents, Female Desogestrel Endometriosis Adult Analysis of Variance Contraceptive Agents, Female Desogestrel Endometriosis Female Humans Middle Aged Pain Measurement Treatment Outcome

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (10)

Source provenance

europepmc
last seen: 2026-09-04T06:17:57.233406+00:00
openalex
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pubmed
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License: CC0 · commercial use OK