Endometriosis: medical and surgical intervention

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For endometriosis, surgery improves pregnancy rates in moderate to severe disease but not mild cases, while medical therapy fails to increase fecundity; both treatments effectively manage pelvic pain, though surgery avoids drug side effects and reduces recurrence.

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Abstract

Pregnancy rates with endometriosis-associated infertility may be improved by laparoscopic surgery or laparotomy for moderate to severe disease. Surgery for minimal to mild disease does not increase pregnancy rates. Medical treatment has not been shown to increase fecundity for any stage of the disease. Pregnancy rates with assisted reproductive technology for endometriosis appear to be comparable with those for tubal disease that are also treated with assisted reproductive technology. Medical and surgical treatments for pelvic pain with endometriosis are both effective, but surgery avoids the side-effects associated with drugs and may result in a lower recurrence rate.

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Condition tags

endometriosisinfertility

MeSH descriptors

Endometriosis Hormones Infertility, Female Laparoscopy Laparotomy Uterine Diseases Combined Modality Therapy Endometriosis Endometriosis Endometriosis Female Hormones Humans Infertility, Female Infertility, Female Infertility, Female Laparoscopy Laparotomy Pregnancy Reproductive Techniques

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Source provenance

europepmc
last seen: 2026-09-21T06:08:07.822426+00:00
pubmed
last seen: 2026-05-13T22:11:02.671803+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine