A double blinded randomized controlled trial to compare Ormeloxifene and Norethisterone in the treatment of Dysfunctional Uterine Bleeding

Chitrangada MS, Satyajeet Kumar Singh, Dr. Prof. Subrata Nag
In: IOSR Journal of Dental and Medical Sciences · 2014 · vol. 13(1) , pp. 52–56 · doi:10.9790/0853-13175256 · W2155888717
article OA: bronze CC0 ⤵ 1 in-corpus citation
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This double-blinded randomized controlled trial compared ormeloxifene and norethisterone for dysfunctional uterine bleeding, assessing changes in menstrual blood loss, hemoglobin, endometrial thickness, and quality of life.

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Abstract

To compare the safety and efficacy of ormeloxifene and norethisterone in treatment of dysfunctional uterine bleeding as measured by decrease in menstrual blood loss using pictorial blood assessment chart. To assess the percentage change in haemoglobin and endometrial thickness before and after treatment. To assess the subjective improvement in life style as evaluated by a five point Likert scale. Methods: A double blinded randomized control trial was conducted on patients attending gynaecology OPD with complaints of menorrhagia with following inclusion criteria women between 18 and 51 years of age, absence of coagulopathies and any pelvic pathology, not taking any drug affecting menstruation, no hormonal therapy in previous three months and normal renal function.

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